Results 141 to 150 of about 1,321,726 (316)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Psychometric Properties of the Serbian Teen Version of the Problem Areas in Diabetes Scale—A Validation Study

Nursing Reports
Screening for diabetes-specific distress should be considered a standard component of diabetes management. This study aimed to evaluate the psychometric properties of the Serbian adaptation of the Problem Areas in Diabetes—Teen Version (PAID-T). Methods:
Mirjana Smudja, Tatjana Milenković, Ivana Minaković, Vera Zdravković, Sandra Mitić, Ana Miljković, Dragana Milutinović   +6 more
doaj   +1 more source

The Behavioural Dyscontrol Scale-Validation of a computerised version in a non-clinical New Zealand population

, 2013
The objective of this study was to evaluate the validity of a new computerised version of the Behavioural Dyscontrol Scale (BDS) in comparison to the original manual version which research has shown to be a sensitive, reliable and valid measure of ...
Kendall, Virginia Ruth
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Adaptation of e-health impact questionnaire into Turkish: a validity and reliability study

Frontiers in Digital Health
Introductione-Health refers to the use of information and communication technologies (ICT) for health-related services. e-Health aims to distribute scarce resources to areas in need more efficiently and to reduce the cost of health care delivery. However,
Mustafa Kafes, Serife Didem Kaya
doaj   +1 more source

Chinese Public Attitudes Toward Epilepsy (PATE) scale: translation and psychometric evaluation

, 2013
None of the quantitative scale for public attitudes toward epilepsy was translated to Chinese language. This study aimed to translate and test the validity and reliability of a Chinese version of the Public Attitudes Toward Epilepsy (PATE) scale. Methods:
Choo, Wan Yuen, Tan, Chong Tin Tan, Hills, Michael, Wu, Cathie, Lim, Kheng Seang   +4 more
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Organizational legitimacy in Latin American higher education: scale development and validation

Cogent Education
The absence of validated measurement instruments for organizational legitimacy in higher education has constrained theoretical advancement and empirical research, particularly in Latin America, where universities face unique legitimacy challenges ...
Leonardo Cañizares-Cedeño, Blanca Estela Hernández Bonilla   +1 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

A Cross-Sectional Dataset for the Validation of an L2 Student Engagement Scale: Evidence from a Vietnamese Context

Journal of Open Humanities Data
This dataset is for the validation of a second language (L2) student engagement scale in the English as a foreign language (EFL) context of Vietnam.
Le Thi Diem Lan, Duong Minh Tuan
doaj   +1 more source