Results 111 to 120 of about 1,959,895 (299)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The Scales Law and the ks=0.22 Constant
This component establishes the definitive mathematical foundation for the Scales Law, providing the first unified energetic framework for hominin survival in subterranean environments. Theoretical Foundation: By integrating the Basal Metabolic Rate (BMR)
Raymond Scales
core +5 more sources
Imagem corporal em homens: instrumentos avaliativos
Psicologia: Teoria e PesquisaEste estudo teve como objetivo avaliar os instrumentos disponíveis para avaliação da imagem corporal de adultos do sexo masculino, bem como verificar as qualidades psicométricas avaliadas no processo de criação/adaptação destes.
Pedro Henrique Berbert de Carvalho +1 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Interview. Matthew Joseph with George Scales (2) [PDF]
, 2010 Interview in which George Scales discusses hill country blues music.
Scales, George, Joseph, Matthew
core
Development of a disease specific quality of life instrument: Thai version of the Diabetic-39
Journal of Health Science and Medical Research (JHSMR), 2009 Objective: To test the validity and reliability of the Thai version of the Diabetes-39 (D-39) instrument. Material and Methods: Translation of the English questionnaire into Thai employed the translation-back translation technique.
K Songraksa, S Lerkiatbundit
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Chancellor Bill Scales' speech at the Centenary Gala Dinner
, 2009 Chancellor Bill Scales talks about the history that has framed Swinburne's evolution from a technical college to a ...
Bill Scales
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source