Results 161 to 170 of about 3,449,394 (355)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Measurement and Its Mathematical Scale [PDF]

open access: yesarXiv, 1998
It is argued that every measurement is made in a certain scale. The scale in which present measuments are made is called present scale which gives present knowledge. Quantities at the limits to present measurement may be observables in other scales. Cantor's series of infinites is used to describe scales of measurement.
arxiv  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Temporal Stability of Soil Moisture and Radar Backscatter Observed by the Advanced Synthetic Aperture Radar (ASAR)

open access: yesSensors, 2008
The high spatio-temporal variability of soil moisture is the result of atmosphericforcing and redistribution processes related to terrain, soil, and vegetation characteristics.Despite this high variability, many field studies have shown that in the ...
Alexander Löw   +9 more
doaj  

Just enough inflation [PDF]

open access: yesarXiv, 2009
We propose a version of chaotic inflation, in which a fundamental scale M, well below the Planck scale M_P, fixes the initial value of the effective potential. If this scale happens to be the scale of grand unified theories, there are just enough e-foldings of inflation.
arxiv  

Rossby and Magnetic Prandtl Number Scaling of Stellar Dynamos

open access: yes, 2019
Rotational scaling relationships are examined for the degree of equipartition between magnetic and kinetic energies in stellar convection zones. These scaling relationships are approached from two paradigms, with first a glance at scaling relationship ...
Augustson, K. ~C.   +2 more
core  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

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