Results 91 to 100 of about 1,697,083 (297)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
On the Fundamental Limits of LLMs at Scale
CoRRLarge Language Models (LLMs) have benefited enormously from scaling, yet these gains are bounded by five fundamental limitations: (1) hallucination, (2) context compression, (3) reasoning degradation, (4) retrieval fragility, and (5) multimodal misalignment.
Mohsin, Muhammad Ahmed +15 more
openaire +3 more sources
Scaling limits of random trees [PDF]
, 2012 We investigate scaling limits of several types of random trees. The study of scaling limits of random trees was initiated by Aldous in the early 1990's. One of the primary goals of his work was to study the uniform distribution on trees with n vertices
Rizzolo, Douglas Paul
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Multidimensional scaling [PDF]
Multidimensional scaling is a statistical technique to visualize dissimilarity data. In multidimensional scaling, objects are represented as points in a usually two dimensional space, such that the distances between the points match the observed ...
Velden, M. van de, Groenen, P.J.F.
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Hidden Adler zeros and soft theorems for inflationary perturbations
Journal of High Energy PhysicsWe derive soft theorems for on-shell scattering amplitudes from non-linearly realised global space-time symmetries, arising from the flat space and decoupling limits of the effective field theories (EFTs) of inflation, while taking particular care of on ...
Zong-Zhe Du
doaj +1 more source
Future Microsystems for Information Processing: Limits and Lessons From the Living Systems
IEEE Journal of the Electron Devices Society, 2013 The paper examines the impact of the physics of extremely scaled information processing devices and systems, with a focus on energy minimization. Architectural implications are also discussed including the impact on system scaling. In order to comprehend
Victor V. Zhirnov, Ralph K. Cavin
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Interpreting a Data Base of Railway Workers using Optimal Scaling Techniques [PDF]
, 2006 Optimal scaling techniques, in particular Categorical Principal Components, are usedin order to interpret the information contained in a database of railway workers.
Fabiola Portillo [0000-0003-3619-9974] +5 more
core
Random Bosonic States for Robust Quantum Metrology
Physical Review X, 2016 We study how useful random states are for quantum metrology, i.e., whether they surpass the classical limits imposed on precision in the canonical phase sensing scenario.
M. Oszmaniec +5 more
doaj +1 more source