Results 101 to 110 of about 1,697,083 (297)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The cloud is the limit: scaling limits of JupyterHub
, 2020 JupyterHub began as a strictly scoped project for "small-scale" Jupyter deployments. Times change. With increasing pressure to scale JupyterHub to ever larger deployments, the current architecture is reaching its limits. See an overview of the current factors limiting JupyterHub's scale what would need to change to make JupyterHub truly scalable ...
openaire +1 more source
Nonanalyticity in Scale in the Planar Limit of QCD
Physical Review Letters, 2012 4 pages, 3 figure, minor adjustments to match version accepted for ...
Lohmayer, R., Neuberger, H.
openaire +4 more sources
Scaling of fracture systems in geological media [PDF]
, 2001 Scaling in fracture systems has become an active field of research in the last 25 years motivated by practical applications in hazardous waste disposal, hydrocarbon reservoir management, and earthquake hazard assessment.
Berkowitz, B. +12 more
core +1 more source
Nature Communications, 2017 Alternative non-volatile memory designs are needed as the scaling of flash-based memories reaches its physical limits. By careful engineering, Xiet al.
Zhongnan Xi +7 more
doaj +1 more source
On the Rarefied Gas Experiments
Entropy, 2019 There are limits of validity of classical constitutive laws such as Fourier and Navier-Stokes equations. Phenomena beyond those limits have been experimentally found many decades ago.
Róbert Kovács
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On the Procrustean analogue of individual differences scaling (INDSCAL) [PDF]
, 2013 In this paper, individual differences scaling (INDSCAL) is revisited, considering INDSCAL as being embedded within a hierarchy of individual difference scaling models.
Gower, John C. +2 more
core +1 more source
Nature Communications, 2016 Molecular electronics holds promise to overcome scaling limits of conventional technologies, but is currently limited to low frequency operation. Here, Trasobares et al.
J. Trasobares +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source