Results 51 to 60 of about 28,638 (292)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The Synthesis and Structure of a Scandium Nitrate Hydroxy-Bridged Dimeric Complex Supported by Bipyridyl Ligands

Molecules, 2022
The current discussion on whether scandium, yttrium and lanthanum should represent Group 3 in the Periodic Table or whether lutetium should replace lanthanum in the group has prompted us to further explore the structural chemistry of the Group 3 elements
Simon A. Cotton, Paul R. Raithby, Stephanie Schiffers, Simon J. Teat, John E. Warren   +4 more
doaj   +1 more source

QED calculation of the 2p1/2-2s and 2p3/2-2s transition energies and the ground-state hyperfine splitting in lithiumlike scandium

, 2007
We present the most accurate up-to-date theoretical values of the {2p_{1/2}}-{2s} and {2p_{3/2}}-{2s} transition energies and the ground-state hyperfine splitting in ${\rm Sc}^{18+}$.
A. N. Artemyev, A. V. Volotka, D. A. Glazov, G. Plunien, I. I. Tupitsyn, N. S. Oreshkina, V. M. Shabaev, V. M. Shabaev, Y. S. Kozhedub   +8 more
core   +1 more source

Chemistry of the Most Metal-poor Stars in the Bulge and the z > 10 Universe [PDF]

, 2014
Metal-poor stars in the Milky Way are local relics of the epoch of the first stars and the first galaxies. However, a low metallicity does not prove that a star formed in this ancient era, as metal-poor stars form over a range of redshift in different ...
Casey, Andrew R., Schlaufman, Kevin C.
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Recovery of Scandium, Aluminum, Titanium, and Silicon from Iron-Depleted Bauxite Residue into Valuable Products: A Case Study

Crystals, 2022
Bauxite residue is a high-iron waste of the alumina industry with significant contents of scandium, aluminum, and titanium. This study focuses on the recovery of Sc, Al, Ti, and Si from iron-depleted bauxite residue (IDBR) into valuable products.
Pavel Grudinsky, Liliya Pasechnik, Anfisa Yurtaeva, Valery Dyubanov, Dmitry Zinoveev   +4 more
doaj   +1 more source

Radioactive Scandium in the Youngest Galactic Supernova Remnant G1.9+0.3

, 2010
We report the discovery of thermal X-ray emission from the youngest Galactic supernova remnant G1.9+0.3, from a 237-ks Chandra observation. We detect strong K-shell lines of Si, S, Ar, Ca, and Fe.
Bamba, Bé, Dupraz, Dwarkadas, Green, Hiraga, Iwamoto, Iyudin, Iyudin, Maeda, Mochizuki, Nagataki, Patil, Protassov, Renaud, Renaud, Reynolds, Reynolds, Slane, Tsunemi, van Dyk, Vink, Yamaguchi   +22 more
core   +1 more source

Intensified processes for FAME production from waste cooking oil: a technological review [PDF]

, 2013
This article reviews the intensification of fatty acid methyl esters (FAME) production from waste cooking oil (WCO) using innovative process equipment. In particular, it addresses the intensification of WCO feedstock transformation by transesterification,
Aubin, Joelle, Mazubert, Alex, Poux, Martine   +2 more
core   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Study on Leaching of Gallium and Scandium from a Gibbsite-Type Bauxite

Kuangchan zonghe liyong
This is an article in the field of metallurgical engineering. There are high contents of gallium and scandium in bauxite, which has great recovery value.
Changju JIANG, Zhanchang LEI, Zhiping FAN   +2 more
doaj   +1 more source