Results 71 to 80 of about 464,622 (269)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Design of Scanning Units for the Underwater Circumferential-Scanning LiDAR Based on Pyramidal-Shaped Reflectors and a Rapid Detection Method for Target Orientation

Remote Sensing
Challenges have been observed in the traditional circumferential-scanning LiDAR underwater to balance between the detection range and the sealing performance.
Bingting Zha, Guangbo Xu, Zhuo Chen, Yayun Tan, Jianxin Qin, He Zhang   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Ship Target Feature Detection of Airborne Scanning Radar Based on Trajectory Prediction Integration

Remote Sensing
In order to address the challenges faced by airborne scanning radars in detecting maritime ship targets, such as low signal-to-clutter ratios and the strong spatio-temporal non-stationarity of sea clutter, this paper proposes a multi-feature detection ...
Fan Zhang, Zhenghuan Xia, Shichao Jin, Xin Liu, Zhilong Zhao, Chuang Zhang, Han Fu, Kang Xing, Zongqiang Liu, Changhu Xue, Tao Zhang, Zhiying Cui   +11 more
doaj   +1 more source

Cervical Twin Heterotopic Pregnancy: Overview of Ectopic Pregnancies and Scanning Detection Algorithm. [PDF]

Medicina (Kaunas), 2021
Koutras A, Fasoulakis Z, Diakosavvas M, Syllaios A, Pagkalos A, Samara AA, Tsatsaris G, Ntounis T, Theodora M, Sindos M, Kontomanolis EN.   +10 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Defect detection method based on sparse scanning with laser ultrasonics

Scientific Reports
The rapid development of metal additive manufacturing (AM) technology has led to its widespread application across various industries, with quality control of AM components being a current focal point of research.
Chenwei Wang, Rui Han, Yihui Zhang, Yuzhong Wang, Yanyang Zi, Jiyuan Zhao   +5 more
doaj   +1 more source

Measurement precision enhancement of surface plasmon resonance based angular scanning detection using deep learning. [PDF]

Sci Rep, 2022
Thadson K, Sasivimolkul S, Suvarnaphaet P, Visitsattapongse S, Pechprasarn S.   +4 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Detection of tumor mass based on laser scanning imaging

مجلة النهرين للعلوم الهندسية, 2017
Optical methods are widely used for medical diagnostic and therapeutic purposes. The use of laser source as non-ionized radiation in the imaging is considered safe, and has advantages more than the other radiological methods The laser application in ...
Munqith S. Dawood, Eman Ghadhban Khalil, Halah Hadi Saleh   +2 more
doaj