Results 61 to 70 of about 362,376 (266)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Possible Luttinger liquid behavior of edge transport in monolayer transition metal dichalcogenide crystals. [PDF]

, 2020
In atomically-thin two-dimensional (2D) semiconductors, the nonuniformity in current flow due to its edge states may alter and even dictate the charge transport properties of the entire device.
Cao, Jingchen, Cao, Yun, Chen, Jiezhi, Chuai, Xichen, Dang, Weiqi, Duan, Xiangfeng, Duan, Xidong, Fan, Zhiqiang, Gao, Hong-Jun, Geng, Di, Huang, Hao, Huang, Yuan, Ji, Zhuoyu, Jiang, Xiangwei, Li, Ling, Liao, Lei, Liu, Liwei, Liu, Ming, Liu, Yuan, Liu, Zhongliu, Lu, Congyan, Lu, Nianduan, Ma, Xiaolei, Niu, Jiebin, Qi, Jing, Shao, Yan, Shi, Xuewen, Wang, Jiawei, Wang, Yeliang, Wei, Wei, Xu, Guangwei, Yang, Guanhua, Zhang, Zhengwei   +32 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

High-Resolution Two-Dimensional Imaging of the 4H-SiC MOSFET Channel by Scanning Capacitance Microscopy

Nanomaterials, 2021
In this paper, a two-dimensional (2D) planar scanning capacitance microscopy (SCM) method is used to visualize with a high spatial resolution the channel region of large-area 4H-SiC power MOSFETs and estimate the homogeneity of the channel length over ...
Patrick Fiorenza, Mario S. Alessandrino, Beatrice Carbone, Alfio Russo, Fabrizio Roccaforte, Filippo Giannazzo   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimension- and shape-dependent thermal transport in nano-patterned thin films investigated by scanning thermal microscopy [PDF]

, 2017
Scanning thermal microscopy (SThM) is a technique which is often used for the measurement of the thermal conductivity of materials at the nanometre scale. The impact of nano-scale feature size and shape on apparent thermal conductivity, as measured using
Dobson, Phillip S., Ge, Yunfei, Weaver, Jonathan M.R., Zhang, Yuan   +3 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Contact resonance frequencies and their harmonics in scanning probe microscopy

IET Science, Measurement & Technology, 2021
Local characterizations of electric, magnetic, mechanical, electrochemical, and structural properties of materials by scanning probe microscopy (SPM) can be carried out by sensing variations of the contact cantilever's resonance frequencies, resulting in
Eduardo A. Murillo‐Bracamontes, Juan J. Gervacio‐Arciniega, Edgar Cruz‐Valeriano, Christian I. Enríquez‐Flores, Martha A. Palomino‐Ovando, José M. Yañez‐Limón, Jesús M. Siqueiros, M. Paz Cruz   +7 more
doaj   +1 more source

Predicting Scattering Scanning Near-field Optical Microscopy of Mass-produced Plasmonic Devices

, 2018
Scattering scanning near-field optical microscopy enables optical imaging and characterization of plasmonic devices with nanometer-scale resolution well below the diffraction limit.
Ashby, Paul D., Burgos, Stanley P., Hammack, Aeron T., Otto, Lauren M., Ren, Shen, Staffaroni, Matteo, Stipe, Barry C., Suzer, Ozgun   +7 more
core   +1 more source

Insulated conducting cantilevered nanotips and two-chamber recording system for high resolution ion sensing AFM. [PDF]

, 2014
Biological membranes contain ion channels, which are nanoscale pores allowing controlled ionic transport and mediating key biological functions underlying normal/abnormal living.
Arce, Fernando Teran, Connelly, Laura S, Lal, Ratnesh, Meckes, Brian   +3 more
core   +2 more sources