Results 51 to 60 of about 348,753 (249)
Scattering Assisted Imaging [PDF]
Scientific Reports, 2019 AbstractStandard imaging systems provide a spatial resolution that is ultimately dictated by the numerical aperture (NA) of the illumination and collection optics. In biological tissues, the resolution is strongly affected by scattering, which limits the penetration depth to a few tenths of microns.
Leonetti M. +4 more
openaire +4 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Neutrons reveal the dynamics of leaf thylakoids in living plants
Scientific ReportsThe study is the first known exploration of photosynthetic membranes dynamics in living plants by high resolution quasielastic neutron scattering spectroscopy.
Laura-Roxana Stingaciu +4 more
doaj +1 more source
Dipolar spin-waves and tunable band gap at the Dirac points in the 2D magnet ErBr3
Communications Physics, 2022 Magnonic devices, based on the physics of spin-waves, are a potential alternative to process and store information that consume less energy and van der Waals crystals are candidate materials for such applications.
Christian Wessler +6 more
doaj +1 more source
American Journal of PhysicsWe discuss the regions forbidden to classical scattering trajectories by repulsive potentials. We give explicit results for the asymptotic form of these regions, far from the scattering center, in terms of the scattering angle function. We account for divergent total cross sections on the basis of these results.
Curtright, Thomas, Verma, Gaurav
openaire +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Rotor–Body Echo Separation Using a Cyclic-Power-Guided Soft Mask from UAV Radar Signals
SensorsRotor-induced micro-Doppler signatures are essential for radar-based characterization of rotary-wing UAVs, but practical echoes are often dominated by a strong quasi-static body return concentrated near zero Doppler.
Ji’er Wang, Jing Sheng, He Tian, Bo Li
doaj +1 more source
Nature Communications, 2020 The SARS-CoV-2 3CL main protease (3CL Mpro) is a chymotrypsin-like protease that facilitates the production of non-structural proteins, which are essential for viral replication and is therefore of great interest as a drug target.
Daniel W. Kneller +8 more
doaj +1 more source