Results 11 to 20 of about 1,335,649 (315)
The Evolution of the Scavenger Receptor Cysteine-Rich Domain of the Class A Scavenger Receptors [PDF]
Frontiers in Immunology, 2015 The class A Scavenger Receptor (cA-SR) family is a group of five evolutionarily related innate immune receptors. The cA-SRs are known for their promiscuous ligand binding; as they have been shown to bind bacteria such as Streptococcus pneumoniae, and ...
Nicholas eYap +3 more
doaj +7 more sources
Standardizing Scavenger Receptor Nomenclature [PDF]
The Journal of Immunology, 2014 Abstract Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a variety of ligands, including endogenous and modified host-derived molecules and microbial pathogens.
PrabhuDas, Mercy +14 more
openaire +5 more sources
Scavenger receptor-BI is a receptor for lipoprotein(a) [PDF]
Journal of Lipid Research, 2013 Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ...
Xiao-Ping Yang +9 more
doaj +3 more sources
The evolution of the class A scavenger receptors [PDF]
BMC Evolutionary Biology, 2012 Background The class A scavenger receptors are a subclass of a diverse family of proteins defined based on their ability to bind modified lipoproteins. The 5 members of this family are strikingly variable in their protein structure and function, raising ...
Whelan Fiona J +4 more
doaj +4 more sources
CXCR7 functions as a scavenger for CXCL12 and CXCL11. [PDF]
PLoS ONE, 2010 BackgroundCXCR7 (RDC1), the recently discovered second receptor for CXCL12, is phylogenetically closely related to chemokine receptors, but fails to couple to G-proteins and to induce typical chemokine receptor mediated cellular responses.
Ulrike Naumann +7 more
doaj +2 more sources
Identification of scavenger receptor BI as a scavenger of free heme that is essential for protection against hemolysis. [PDF]
Nat CommunIto M +18 more
europepmc +4 more sources
Scavenger Receptor CD163 and Its Biological Functions
Acta Medica, 2009 CD163 is a member of scavenger receptor super family class B of the first subgroup. It is mapped to the region p13 on chromosome 12. Five different isoforms of CD163 have been described, which differ in the structure of their cytoplasmic domains and ...
Gabriela Onofre +3 more
doaj +2 more sources
Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen [PDF]
Nature Communications, 2023 The opportunistic fungal pathogen Cryptococcus neoformans causes lethal infections in immunocompromised patients. Macrophages are central to the host response to cryptococci; however, it is unclear how C.
Chinaemerem U. Onyishi +10 more
doaj +2 more sources
Deletion of the murine scavenger receptor CD68[S] [PDF]
Journal of Lipid Research, 2011 Scavenger receptors (ScRs) are a structurally unrelated family of receptors with the ability to bind modified low density lipoprotein (LDL) as well as a broad range of polyanionic ligands.
Li Song +2 more
doaj +4 more sources
Tumor Biology, 2017 Aberrant expression of scavenger receptor class B type 1 has been reported in several human cancers. Nevertheless, the roles of scavenger receptor class B type 1 in clear cell renal cell carcinoma remain unclear. The aim of this study was to evaluate the
Guanghua Xu +13 more
doaj +2 more sources