Results 141 to 150 of about 862,152 (305)
Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan+6 more
wiley +1 more source
SR-BI-directed HDL-cholesteryl ester hydrolysis
We have examined the metabolic fate of HDL cholesteryl ester (CE) delivered to cells expressing scavenger receptor class B type I (SR-BI). Comparison of SR-BI with a related class B scavenger receptor, CD36, showed a greater uptake and a more rapid and ...
Margery A. Connelly+3 more
doaj
Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice [PDF]
Ruud Out+7 more
openalex +1 more source
A novel interpenetrating network hydrogel microsphere (NSC‐Exos@HIMS) is developed to manipulate oxygen tension in damaged regions and recruit endogenous stem cells. In vitro and in vivo results show that NSC‐Exos@HIMS maintains the hypoxia microenvironment for up to 5 days, which triggers nucleus pulposus cell‐like differentiation and enhanced ECM ...
Xingdie Zhou+9 more
wiley +1 more source
Lipid metabolism in pancreatic cancer: emerging roles and potential targets
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin+6 more
wiley +1 more source
Cellular SR-BI and ABCA1-mediated cholesterol efflux are gender-specific in healthy subjectss⃞
We evaluated the impact of gender differences in both the quantitative and qualitative features of HDL subspecies on cellular free cholesterol efflux through the scavenger receptor class B type I (SR-BI), ABCA1, and ABCG1 pathways.
Giovanna Catalano+6 more
doaj
Targeting of Scavenger Receptor Class B Type I by Synthetic Amphipathic α-Helical-containing Peptides Blocks Lipopolysaccharide (LPS) Uptake and LPS-induced Pro-inflammatory Cytokine Responses in THP-1 Monocyte Cells [PDF]
Alexander V. Bocharov+7 more
openalex +1 more source
A new kind of selenium‐doped Ag/Ag2S Janus nanoparticles (Ag/Ag2SexSy JNPs) is reported as radio‐responsive probes for specifically hydrogen peroxide (H2O2)‐activated cancer imaging and enhanced radiosensitization, offering a promising approach for precision cancer theranostics.
Kang Zhu+12 more
wiley +1 more source
Dual Role for Scavenger Receptor Class B, Type I on Bone Marrow-Derived Cells in Atherosclerotic Lesion Development [PDF]
Miranda Van Eck+4 more
openalex +1 more source