The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang+6 more
wiley +1 more source
CD36 does not play a direct role in HDL or LDL metabolism
CD36 and scavenger receptor class B, type I (SR-BI) are both class B scavenger receptors that recognize a broad variety of ligands, including oxidized low density lipoprotein (oxLDL), HDL, anionic phospholipids, and apoptotic cells.
Willem J.S. de Villiers+5 more
doaj
Scavenger receptor class B, type I (SR-BI) homo-dimerizes via its C-terminal region: Fluorescence resonance energy transfer analysis [PDF]
Daisy Sahoo+4 more
openalex +1 more source
The Molecular Basis of Amino Acids Sensing
Amino acids are essential as protein building blocks and signaling molecules, enabling metabolic regulation. Cells sense amino acid levels to control protein synthesis, maintain homeostasis, and adapt to nutritional changes. This review explores recent advances in amino acid sensing mechanisms across organisms, highlighting their roles in cellular ...
Cong Jiang+3 more
wiley +1 more source
Cholesterol-metabolism-associated molecules, including scavenger receptor class A (SR-A), lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), CD36, ACAT1, ABCA1, ABCG1, and scavenger receptor class B type I, can modulate cholesterol ...
Yong Yang+12 more
doaj
Cell-Specific Polymorphism and Hormonal Regulation of DNA Methylation in Scavenger Receptor Class B, Type I. [PDF]
Hu Z+5 more
europepmc +1 more source
The Transcriptional Factor Prolactin Regulatory Element-Binding Protein Mediates the Gene Transcription of Adrenal Scavenger Receptor Class B Type I via 3′,5′-Cyclic Adenosine 5′-Monophosphate [PDF]
Koji Murao+9 more
openalex +1 more source
Protein deglycosylation can drastically affect the cellular uptake [PDF]
Ghazaryan, A.+2 more
core +2 more sources
Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao+8 more
wiley +1 more source
The thyromimetic T-0681 protects from atherosclerosis
This report describes studies in hyperlipidemic New Zealand White (NZW) rabbits investigating the impact of the liver-selective thyromimetic T-0681 on lipoprotein metabolism and the development of atherosclerosis.
Ivan Tancevski+16 more
doaj