Results 241 to 250 of about 38,420,644 (271)

HDL scavenger receptor class B type I and platelet function

Current Opinion in Lipidology, 2011
HDL cholesterol levels have been inversely correlated with thrombosis and HDL has been shown to mediate various antithrombotic effects. However, molecular mechanisms underlying the suppressing effect of HDL on platelet reactivity are not completely understood.
Jerzy-Roch, Nofer, Miranda, van Eck
openaire   +2 more sources

HDL and Scavenger Receptor Class B Type I (SRBI)

2022
The scavenger receptor class B type I (SR-BI) is a versatile HDL receptor protein. It is highly expressed in liver and steroidogenic tissues. SR-BI regulates selective uptake of cholesterol ester (CE) from HDL, revealing its role in mediating reverse cholesterol transport (RCT) and steroid hormone synthesis.
openaire   +2 more sources

Upregulation of scavenger receptor class B type I expression by activation of FXR in hepatocyte

Atherosclerosis, 2010
The farnesoid X receptor (FXR), a member of the nuclear receptor superfamily, has been proposed to play an important role in the pathogenesis of cardiovascular diseases by regulating the metabolism and transport of cholesterol and triglyceride. Scavenger receptor class B type I (SR-BI), a high-density lipoprotein receptor, plays an important role in ...
Ramalinga Kuruba, Yingru Zheng
exaly   +3 more sources

Activation of the rat scavenger receptor class B type I gene by PPARα

Molecular and Cellular Endocrinology, 2006
Peroxisomal proliferator activated receptor alpha (PPARalpha) is activated by fibrate drugs which are known to protect against atherosclerosis. The present study examines the effects of PPARalpha on SR-BI expression. For this study, a rat SR-BI promoter-luciferase reporter gene construct was co-transfected into different cell lines with expression ...
Dayami, Lopez, Mark P, McLean
openaire   +2 more sources

Scavenger receptor class B type I polymorphisms and peripheral arterial disease

Metabolism, 2007
Genetic variations of the scavenger receptor class B type I (SR-BI) have been demonstrated to be associated with plasma lipid parameters, anthropomorphic parameters, and coronary artery disease. We determined the frequency of 3 single-nucleotide polymorphisms within the SR-BI gene (SCARB1) in 354 patients with peripheral arterial disease (PAD) and 354 ...
Andreas, Ritsch, Gudrun, Sonderegger, Gudron, Sonderegger, Anton, Sandhofer, Ursula, Stanzl, Ursala, Stanzl, Ivan, Tancevski, Philipp, Eller, Wilfried, Schgoer, Andreas, Wehinger, Thomas, Mueller, Meinhard, Haltmayer, Josef R, Patsch, Joseph R, Patsch   +13 more
openaire   +2 more sources

Stabilization of Caveolin-1 by Cellular Cholesterol and Scavenger Receptor Class B Type I

Biochemistry, 2002
Caveolae are 50-100 nm plasma membrane invaginations, which function in cell signaling, in transcytosis, and in regulating cellular cholesterol homeostasis. These subcompartments of the plasma membrane are characterized by the presence of caveolin proteins.
Philippe G, Frank, Yves L, Marcel, Margery A, Connelly, Douglas M, Lublin, Vivian, Franklin, David L, Williams, Michael P, Lisanti   +6 more
openaire   +2 more sources

Characterization of scavenger receptor class B, type I in Atlantic salmon (Salmo salar L.)

Lipids, 2006
AbstractThe scavenger receptor class B, type I (SR‐BI) is an important player in regulation of mammalian lipid homeostasis. We therefore wanted to study this receptor in Atlantic salmon (Salmo salar L.), which requires a diet with particular high lipid content. We have for the first time cloned and characterized SR‐BI from a salmonid fish.
E J, Kleveland, B L, Syvertsen, B, Ruyter, A, Vegusdal, S M, Jørgensen, T, Gjøen   +5 more
openaire   +2 more sources

Scavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression

Neurochemical Research
Scavenger receptor class B type I (SR-BI) is abundant in adult mouse and human brains, but its function in the central nervous system (CNS) remains unclear. This study explored the role of SR-BI in epilepsy and its possible underlying mechanism. Expression patterns of SR-BI in the brains of mice with kainic acid (KA)-induced epilepsy were detected ...
Yunyi, Huang, Yuan, Gao, Zhongwen, Huang, Minxue, Liang, Yangmei, Chen   +4 more
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Rosuvastatin attenuates atherosclerosis in rats via activation of scavenger receptor class B type I

European Journal of Pharmacology, 2014
In order to investigate the effect and mechanism of action of rosuvastatin on atherosclerotic lesion in a Wistar rat model, 16 Wistar rats were fed a cholesterol-rich, vitamin D3 overload diet and underwent balloon injury of the aorta. One day prior to injury, half of the rats began rosuvastatin treatment (5mg/kg/d) via oral gavage.
Yonghong, Li, Qixin, Wang, Jingwei, Zhou, Qingke, Xu, Xianming, Chu, Tingru, Sun, Xu, Liu, Shanglang, Cai   +7 more
openaire   +2 more sources

The Scavenger Receptor Class B Type I

2010
Aishah Al-Jarallah, Rachelle Brunet, Bernardo Trigatti   +2 more
openaire   +1 more source