The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding
Lectin-like oxidized LDL (ox-LDL) receptor-1 (LOX-1) is a type-II transmembrane protein that belongs to the C-type lectin family of molecules. LOX-1 acts as a cell surface endocytosis receptor and mediates the recognition and internalization of ox-LDL by
Omar L. Francone+10 more
doaj
Role of the scavenger receptor in the uptake of methylamine-activated α2-macroglobulin by rat liver [PDF]
M.C.M. van Dijk+3 more
openalex +1 more source
A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu+10 more
wiley +1 more source
Polymorphism of class A scavenger receptors in C57BL/6 mice1
Scavenger receptors class A (SR-A) have been hypothesized to regulate the development of atherosclerotic lesions through recognition of modified low density lipoprotein (LDL) and macrophage adhesion to substrata.
Alan Daugherty+3 more
doaj
Corrigendum to "The effective transfection of a low dose of negatively charged drug-loaded DNA-nanocarriers into cancer cells via scavenger receptors"[Journal of Pharmaceutical Analysis volume 11 (2021) 174-182]. [PDF]
Baig MMFA+4 more
europepmc +1 more source
Nanotherapy for Neural Retinal Regeneration
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu+11 more
wiley +1 more source
Modulation of macrophage scavenger receptor transport by protein phosphorylation
The identification of three highly conserved phosphorylation sites in the cytoplasmic domain of each of the monomeric subunits of the macrophage scavenger receptor suggests that protein phosphorylation may regulate this receptor pathway.
L G Fong
doaj
Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors. [PDF]
Kulkarni NN+5 more
europepmc +1 more source
Human mesangial cells express inducible macrophage scavenger receptor [PDF]
Xiong Z. Ruan+3 more
openalex +1 more source
DNA Origami‐Cyanine Nanocomplex for Precision Imaging of KRAS‐Mutant Pancreatic Cancer Cells
DNA origami‐cyanine (Do‐Cy) nanocomplexes are synthesized to selectively image KRAS‐mutant pancreatic cancer cells in the highly desmoplastic tumors. This study shows that the Do‐Cy nanocomplexes are preferentially internalized by cancer cells over other stroma cells via KRAS‐dependent macropinocytosis.
Hye‐ran Moon+7 more
wiley +1 more source