Results 161 to 170 of about 53,683 (320)

Role of the Scavenger Receptor MARCO in Alveolar Macrophage Binding of Unopsonized Environmental Particles [PDF]

open access: bronze, 1999
Aiyappa Palecanda   +9 more
openalex   +1 more source

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

open access: yesAdvanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao   +15 more
wiley   +1 more source

The Battle of LPS Clearance in Host Defense vs. Inflammatory Signaling

open access: yesCells
Lipopolysaccharide (LPS) in blood circulation causes endotoxemia and is linked to various disease conditions. Current treatments focus on preventing LPS from interacting with its receptor Toll-like receptor 4 (TLR4) and reducing inflammation.
Pankaj Kumar   +4 more
doaj   +1 more source

Expression Cloning of a Novel Scavenger Receptor from Human Endothelial Cells [PDF]

open access: hybrid, 1997
Hideki Adachi   +3 more
openalex   +1 more source

A Tailored Hydrogel With Local Glycemia Management, Antioxidant Activity, and Photothermal Antibacterial Properties for Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A multifunctional wound dressing (ACG gels) with antioxidant, local glycocontrol, and antibacterial properties to promote diabetic wound healing. Au‐CeO2 dumbbells effectively eliminate ROS, protecting cells from oxidative stress‐induced damage while exhibiting significant near‐infrared photothermal antibacterial activity.
Bangguo Zhou   +9 more
wiley   +1 more source

Ultrasound‐Assisted H2 Transmitter Enables Hydrogen‐Gene Therapy to Prevent Anesthesia/Surgery‐Induced Cognitive Impairment

open access: yesAdvanced Science, EarlyView.
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan   +11 more
wiley   +1 more source

Binding Selectivity Analysis from Alchemical Receptor Hopping and Swapping Free Energy Calculations [PDF]

open access: yesarXiv
We present receptor hopping and receptor swapping free energy estimation protocols based on the Alchemical Transfer Method (ATM) to model the binding selectivity of a set of ligands to two arbitrary receptors. The receptor hopping protocol, where a ligand is alchemically transferred from one receptor to another in one simulation, directly yields the ...
arxiv  

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