Results 61 to 70 of about 8,997 (201)

Host–Pathogen Dual Targeting With Repurposed Drugs Identifies a Synergistic Therapy for Intracellular Staphylococcus aureus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
A large intracellular drug‐repurposing screen identifies a potent synergy between 5‐fluoro‐2′‐deoxycytidine and rifapentine, acting through dual host–pathogen targeting to reduce Staphylococcus aureus burdens across strains, cell types, and infection models (created with BioRender).
Blanca Lorente‐Torres, Helena Á. Ferrero, Pablo Castañera, Jesús Llano‐Verdeja, Sergio Fernández‐Martínez, Amanda Herrero‐González, Farzaneh Javadimarand, Roberto López, Jesús F. Aparicio, Andrew M. Edwards, Volker Behrends, Luis M. Mateos, Álvaro Mourenza, Michal Letek   +13 more
wiley   +1 more source

Staphylococcus aureus as Food-Borne Disease: An Ongoing Threat in Public Health in the Kingdom of Saudi Arabia

Journal of Pure and Applied Microbiology, 2023
Majority of the global population have been affected by food-borne diseases, and Staphylococcus aureus is one of the causes of this disease. S. aureus can be transmitted through contaminated food and is a risk to universal human health because of its ...
Mashael Alghizzi, Ashwag Shami
doaj   +1 more source

Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Zurich, Switzerland (2003): prevalence of type IV SCCmec and a new SCCmec element associated with isolates from intravenous drug users

, 2005
The majority of methicillin-resistant Staphylococcus aureus (MRSA) isolates, recovered in 2003 at the Department of Medical Microbiology in Zürich, Switzerland, belonged to major clones that are circulating worldwide.
Imhof, Alexander, Ender, Miriam, O'Brien, Frances, McCallum, Nadine, Berger-Bächi, Brigitte, Ruef, Christian, Qi, Wei   +6 more
core   +1 more source

One Health Genomic Analysis of Methicillin‐Resistant Staphylococcus spp. From Humans, Cats, and Dogs in a Veterinary Hospital in Central Chile

Zoonoses and Public Health, Volume 73, Issue 3, Page 205-217, May 2026.
ABSTRACT Introduction The emergence of methicillin‐resistant Staphylococcus species (MRS) poses a growing threat to both human and veterinary health. Methods We performed a comparative genomic characterisation of 49 methicillin‐resistant Staphylococcus isolates collected from humans, dogs, and cats in a veterinary hospital from Central Chile.
Daniel Garrido, Danny Fuentes‐Castillo, Leslye Camila del Río, Jorge Barraza‐Schulmeyer, Felipe Melis, Patricia García, Carla Flores‐Yáñez, Pamela Thomson   +7 more
wiley   +1 more source

Strategies of adaptation of Staphylococcus epidermidis to hospital and community: amplification and diversification of SCCmec [PDF]

Journal of Antimicrobial Chemotherapy, 2012
Staphylococcus epidermidis is a harmless commensal, but it can become a human pathogen, mainly in the hospital environment. In order to clarify strategies used by these bacteria to adapt to the hospital environment, we compared the population structure and staphylococcal cassette chromosome mec (SCCmec) content of S.
Rolo, J., de Lencastre, H., Miragaia, M.
openaire   +2 more sources

Genetic and phenotypic diversity of methicillin-resistant Staphylococcus aureus among Japanese inpatients in the early 1980s

Scientific Reports, 2021
To trace the linkage between Japanese healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) strains in the early 1980s and the 2000s onward, we performed molecular characterizations using mainly whole-genome sequencing.
Hui Zuo, Yuki Uehara, Yujie Lu, Takashi Sasaki, Keiichi Hiramatsu   +4 more
doaj   +1 more source

Association between SCCmec types and antimicrobial resistance in clinical MRSA isolates [PDF]

, 2022
Background: Methicillin resistant Staphylococcus aureus (MRSA) is the causative agent of serious infections. MRSA isolates carry mecA gene which confers resistance to all β-lactams, markedly limiting the therapeutic options ...
Aboulela, Aliaa, Roufaeil, Mirette, Kader, Ola, Rezk, Shahinda   +3 more
core  

The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2023–2024

EFSA Journal, Volume 24, Issue 2, February 2026.
Abstract This report presents the main findings of the 2023–2024 harmonised antimicrobial resistance (AMR) monitoring in Salmonella spp., Campylobacter jejuni and Campylobacter coli from humans, food‐producing animals (broilers, laying hens, fattening turkeys, fattening pigs and bovines under 1 year of age), and derived meat.
European Food Safety Authority (EFSA), European Centre for Disease Prevention and Control (ECDC)   +1 more
wiley   +1 more source

Phenotypic and Genotypic Analyses of Antimicrobial Resistance Patterns of Staphylococcus aureus Isolates From Outpatient Blood Samples in Mukuru Slum, Nairobi, Kenya

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background Bloodstream infections caused by Staphylococcus aureus (S. aureus) and its methicillin‐resistant S. aureus (MRSA) represent a major clinical challenge, contributing to prolonged illness, increased healthcare costs, and high mortality worldwide. In low‐resource settings, these infections are further aggravated by overcrowding, poor sanitation,
Jeremiah Ogeto, Simon Mitema, Gabriel Aboge, Alfred Mainga, Gervason Moriasi, Mian Muhammad Awais   +5 more
wiley   +1 more source

Methicillin-resistant Staphylococcus lugdunensis carrying SCCmec type V misidentified as MRSA [PDF]

The Brazilian Journal of Infectious Diseases, 2011
Staphylococcus lugdunensis is a rare cause of severe infections and clinical manifestations are similar to those related to S. aureus infection. We describe a hospital-acquired bacteremia due to methicillin-resistant Staphylococcus lugdunensis, misidentified as methicillin-resistant S. aureus. The oxacillin MIC was 16 µg/mL and the mecA gene and SCCmec
Eliezer Menezes Pereira, Ricardo Pinto Schuenck, Simone Aranha Nouér, Kátia Regina Netto dos Santos   +3 more
openaire   +4 more sources