In Vitro Activity of the Novel Antifungal Olorofim against Scedosporium and Lomentospora prolificans
Scedosporium spp. and Lomentospora prolificans are an emerging group of fungi refractory to current antifungal treatments. These species largely affect immunocompromised individuals but can also be lung colonizers in cystic fibrosis patients.
Ourania Georgacopoulos +5 more
doaj +1 more source
Scedosporium apiospermum chorioretinitis [PDF]
ABSTRACT.Purpose: A case of a 24‐year‐old immunocompetent woman who developed unilateral Scedosporium apiospermum chorioretinitis and diffuse cervical lymphadenitis 10 years after facial steroid injection is described.Methods: The patient was initially treated for the misdiagnosis of tuberculous lymphadenitis.
H, Kiratli, , Uzun O, N, Kiraz, B, Eldem
openaire +2 more sources
Environmental Screening for the Scedosporium apiospermum Species Complex in Public Parks in Bangkok, Thailand. [PDF]
The Scedosporium apiospermum species complex, comprising filamentous fungal species S. apiospermum sensu stricto, S. boydii, S. aurantiacum, S. dehoogii and S. minutispora, are important pathogens that cause a wide variety of infections.
Natthanej Luplertlop +4 more
doaj +1 more source
Monoclonal antibodies against peptidorhamnomannans of Scedosporium apiospermum enhance the pathogenicity of the fungus. [PDF]
Scedosporium apiospermum is part of the Pseudallescheria-Scedosporium complex. Peptidorhamnomannans (PRMs) are cell wall glycopeptides present in some fungi, and their structures have been characterized in S. apiospermum, S.
Livia C L Lopes +8 more
doaj +1 more source
Scedosporium apiospermumkeratitis treated with itraconazole [PDF]
Mycotic keratitis usually occurs in conjunction with trauma to the cornea. Scedosporium apiospermum, a dematiaceous fungus linked to the teleomorph Pseudallescheria boydii is not a common agent of mycotic keratitis. A 22-year old male patient with mycotic keratitis due to S. apiospermum is presented.
M A, Saracli +3 more
openaire +2 more sources
We report the use of voriconazole troughs to achieve appropriate therapeutic levels in treatment of a cutaneous Scedosporium apiospermum infection. Following heart transplantation, a 63-year-old immunocompromised patient presented with post-traumatic ...
McKenna E. Boyd +4 more
doaj +1 more source
Species of the genus Scedosporium (family Microascaceae, phylum Ascomycota) are responsible for a wide range of opportunistic human infections, and have a low susceptibility to most antifungal drugs.
Ruben A. Abrantes +10 more
doaj +1 more source
Draft Genome Sequence of the Human-Pathogenic Fungus Scedosporium boydii [PDF]
The opportunistic fungal pathogen Scedosporium boydii is the most common Scedosporium species in French patients with cystic fibrosis. Here we present the first genome report for S.
Bouchara, J-P. +8 more
core +3 more sources
Scedosporium apiospermum endopthalmitis treated early with intravitreous voriconazole results in recovery of vision [PDF]
AIM: The purpose of this study is to report a case of endogenous endopthalmitis caused by Scedosporium apiospermum with a favorable outcome and review previously reported cases, their treatment regimens and outcomes.
Catherine Liu +2 more
core +1 more source
Absence of intraocular infections after hematopoietic stem cell transplantation at a single center: The experience with current preventive regimens [PDF]
Purpose: To investigate the prevalence of intraocular infections after allogeneic stem cell transplantation (allo-SCT). Methods: The study design was a single institutional retrospective noncomparative cohort of 135 consecutive patients in 2006 and 2007 ...
Boome, L.C.J. (Liane ) te +4 more
core +1 more source

