Results 51 to 60 of about 1,543,904 (315)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Frontiers in Complex SystemsThe global socio-ecological system in the era of the Capitalocene—the world system created by the use of fossil fuels to provide energy for the development of a growth-oriented capitalist logic in all areas of production and consumption—is facing a set ...
David Sidney Byrne
doaj +1 more source
Critical thinking perspectives of undergraduate students
Advancements in Agricultural Development, 2020 Today’s learners need support in not only developing capacity for a global mindset, but also for thinking critically about the world. Employers are seeking graduates who can enter the workforce prepared to work within agriculture with the ability to ...
Nicole Stedman, Amy Brown
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Culture and climate change scenarios: The role and potential of the arts and humanities in responding to the ‘1.5 degrees target’ [PDF]
, 2018 This paper critically assesses the role and potential of the arts and humanities in relation to the ‘1.5 degree target’ embedded within the Paris Agreement.
Tyszczuk, R.A. +5 more
core +1 more source
Scenario Modelling of University International Activities Based on Fuzzy Cognitive Maps
Proceedings of the International Conference on Applied Innovations in ITIn this article the concept of managing the effectiveness of international activities of universities based on fuzzy cognitive maps is discussed. The focus on the international relations currently plays an important role in almost all universities, as ...
Anastasia Krivtsun, Daria Kushchiy
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 2018 <p>This repository is part of an ongoing effort to simulate nuclear fuel cycle transition scenarios in Cyclus, the agent-based fuel cycle simulator.
Jin Whan Bae +5 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The Role of Transdisciplinary Research for Agricultural Climate Change Adaptation Strategies
Agronomy, 2018 While science widely acknowledges the necessity of climate change adaptation (CCA), concrete strategies for CCA by major land-use actor groups at a local level are largely missing.
Markus Schermer +6 more
doaj +1 more source