Results 61 to 70 of about 1,543,904 (315)

Conventional Methods in Housing Market Analysis: A Review of Literature

open access: yesBaltic Journal of Real Estate Economics and Construction Management, 2020
Housing market analysis has witnessed considerable changes in recent decades, especially as a result of the complexity of human settlements and the dynamics of property market analytical techniques.
Bello Musa Zango   +2 more
doaj   +1 more source

Modeling Spatial Charging Demands Related to Electric Vehicles for Power Grid Planning Applications

open access: yesISPRS International Journal of Geo-Information, 2020
The electrification of the transport sector together with an increasing share of renewable energies has the potential to reduce CO2 emissions significantly. This transformation requires the rollout of charging infrastructure, which has an impact on power
Philip Gauglitz   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Scenarios and counterfactuals as modal narratives

open access: yes, 2009
Scenarios and counterfactuals are two types of modal narrative. Modal narratives concern themselves with contingency and determinism: with questions of possibility and necessity.
Booth, Charles   +4 more
core   +1 more source

ISS-Scenario: Scenario-Based Testing in CARLA

open access: yes
The rapidly evolving field of autonomous driving systems (ADSs) is full of promise. However, in order to fulfil these promises, ADSs need to be safe in all circumstances. This paper introduces ISS-Scenario, an autonomous driving testing framework in the paradigm of scenario-based testing.
Renjue Li   +2 more
openaire   +2 more sources

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Macroecology meets IPBES

open access: yesFrontiers of Biogeography, 2016
The Intergovernmental Platform for Biodiversity and Ecosystem Services (IPBES), established in 2012 to counter the biodiversity crisis, requires the best scientific input available to function as a successful science-policy interface that addresses the ...
Christian Hof   +10 more
doaj  

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