Results 81 to 90 of about 5,220,122 (327)

Distinguishing among Technicolor/Warped Scenarios in Dileptons [PDF]

open access: yes, 2011
Models of dynamical electroweak symmetry breaking usually include new spin-1 resonances, whose couplings and masses have to satisfy electroweak precision tests.
A Falkowski   +60 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Food System Scenarios in Uncertain Futures: A Case Study on Long-Term Local Food System Planning in Revelstoke, Canada

open access: yesAgriculture
Scenario planning is a potentially effective method for supporting long-term planning for sustainable and resilient food systems; however, scenario exercises are often limited by too much focus on a single preferred future, not accounting for uncertainty
Robert Newell   +3 more
doaj   +1 more source

Global emissions pathways under different socioeconomic scenarios for use in CMIP6: a dataset of harmonized emissions trajectories through the end of the century

open access: yesGeoscientific Model Development, 2018
. We present a suite of nine scenarios of future emissions trajectories of anthropogenic sources, a key deliverable of the ScenarioMIP experiment within CMIP6.
M. Gidden   +22 more
semanticscholar   +1 more source

Generating VaR scenarios with product beta distributions [PDF]

open access: yes, 2018
We propose a Monte Carlo simulation method to generate stress tests by VaR scenarios under Solvency II for dependent risks on the basis of observed data.
Pfeifer, Dietmar, Ragulina, Olena
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Design of an Efficient Model for Psychological Disease Analysis and Prediction Using Machine Learning and Genomic Data Samples

open access: yesBig Data and Cognitive Computing
There is a rapid growth in mental disorders, thus leading to a pressing demand for more sophisticated diagnosis techniques. Clinical assessments and symptomatic analyses for traditional diagnostics suffer from subjectivity, delayed diagnosis, and ...
Alparthi Kumuda, Saroj Kumar Panigrahy
doaj   +1 more source

Global energy perspectives to 2060 – WEC's World Energy Scenarios 2019

open access: yes, 2020
The recent signals in the energy sector indicate a major transformation taking shape in the energy sector in the decades to come. The potential trends are highlighted in three scenarios published by the World Energy Council in September 2019 and further ...
T. Kober   +3 more
semanticscholar   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Scenarios—using the complexity frame of reference to inform the construction of available futures in the possibility space

open access: yesFrontiers in Complex Systems
The global socio-ecological system in the era of the Capitalocene—the world system created by the use of fossil fuels to provide energy for the development of a growth-oriented capitalist logic in all areas of production and consumption—is facing a set ...
David Sidney Byrne
doaj   +1 more source

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