Results 111 to 120 of about 32,466 (306)

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

open access: yesAdvanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen   +15 more
wiley   +1 more source

“Policy Scepticism” and the Impact of Welsh Higher Education Institutions (HEIs) on their Host Region: Accounting for Regional Budget Constraints [PDF]

open access: yes
This paper replicates the analysis of Scottish HEIs in Hermannsson et al (2010b) for the case of Wales in order to provide a self-contained analysis that is readily accessible by those whose primary concern is with the regional impacts of Welsh HEIs.
Kristinn Hermannsson   +3 more
core  

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

open access: yesAdvanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li   +5 more
wiley   +1 more source

Ancient Scepticism

open access: yesAestimatio, 2015
Harald Thorsrud (book author)   +1 more
doaj   +1 more source

On the Problem of Truth and Certainty in Epistemology: a Conceptual Consideration

open access: yesФілософія освіти
Relevance. The two central and interrelated issues in epistemology are the problem of truth and the problem of certainty. These have occupied the interest of philosophical debate whether human beings can know anything with absolute certainty and what it ...
Funmilayo Arinola Ade-Ali
doaj   +1 more source

PhosSight: A Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

open access: yesAdvanced Science, EarlyView.
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang   +10 more
wiley   +1 more source

Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption

open access: yesAdvanced Science, EarlyView.
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang   +6 more
wiley   +1 more source

Must Phenomenology be Transcendental?

open access: yesFelsefe Arkivi
An example of criticism of the transcendental character of phenomenology from within the phenomenological movement has recently been presented by Claude Romano. I argue against Romano’s criticism.
Eylem Hacımuratoğlu
doaj   +1 more source

FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model

open access: yesAdvanced Science, EarlyView.
FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble   +9 more
wiley   +1 more source

Consumer scepticism [PDF]

open access: yes
This chapter provides an overview of the literature on consumer scepticism. It begins by defining the term and distinguishing it from other related phenomena, such as cynicism and distrust. The chapter provides insight into the emergence of scepticism in
Dunn, Katie
core   +1 more source

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