Results 101 to 110 of about 51,375 (256)

Harnessing Lactobacillus-derived SCFAs for food and health: Pathways, genes, and functional implications

Current Research in Microbial Sciences
Short-chain fatty acids (SCFAs) are crucial microbial metabolites that mediate host–microbiota interactions, regulate immune responses, and maintain gut homeostasis.
Yousef Nami, Milad Shaghaghi Ranjbar, Mahmoudreza Modarres Aval, Babak Haghshenas   +3 more
doaj   +1 more source

Short-chain fatty acid (SCFA) production maximization by modeling thermophilic sludge fermentation

, 2019
Producing more versatile green chemicals such as short-chain fatty acids (SCFAs) from waste activated sludge (WAS) via fermentation is a promising approach in wastewater treatment.
Zuo, Zhiqiang, Shi, Hanchang, Huang, Xia, Liu, Yanchen, Xiong, Huilei, Zheng, Min   +5 more
core   +1 more source

Effects of an Organic Acid Blend on Growth Performance, Redox Homeostasis, and Intestinal Microbiota of Broilers in an Antibiotic‐Free Production System Under Winter Environmental Challenges

Animal Research and One Health, EarlyView.
Schematic summary of the effects of organic acids on growth performance and gut health‐related parameters in broilers. ABSTRACT This study was conducted to evaluate the effects of an organic acid blend on growth performance, redox homeostasis, and intestinal microbiota of broilers raised in an antibiotic‐free system during the winter season in China ...
Rong‐Hui Huang, Hong‐Lin Li, Yu Zhang, Jie Wang, Shao‐Qing Wang, Xue‐Wu Li, Lane Pineda, Xiang‐Dong Kuang, Giseli Heim, Mahmoud Mohamed Khalil, Lv‐Hui Sun, Zhang‐Chao Deng   +11 more
wiley   +1 more source

Effect of statins on SCFA production after fermentation.

, 2020
Acetic, propionic, isobutyric, butyric, isovaleric, and valeric acid were detected using GC in this paper. Each sample was measured in triplicate. Figures were generated using GraphPad Prism version 5.01.
Jinlan Xia (8626125), Yunfei Hu (358370), Changhui Zhao (634155), Yeshi Yin (449206), Baiyuan Li (639365), Linyan Cao (8626122), Huahai Chen (3723496)   +6 more
core   +1 more source

Effects of Dietary Mannan Oligosaccharides on Growth, Disease Resistance, and Gut Microbiota in Zebrafish

Animal Research and One Health, EarlyView.
Supplementation with mannan oligosaccharides (MOS) enhances growth, disease resistance, antioxidant capacity, and gut microbiota diversity while suppressing inflammation, apoptosis, and strengthening intestinal barrier integrity in zebrafish challenged with LPS or DSS.
Zhiyuan Lu, Longjiang Tang, Lei Deng, Ziheng Ren, Zhiyuan Gong   +4 more
wiley   +1 more source

Spicy food intake and dietary factors shape the gut microbiome and metabolism of mucin and short-chain fatty acids in healthy adults

Scientific Reports
Whether spicy food intake independently modulates mucin metabolism and short-chain fatty acid (SCFA) production or depends on co-ingested factors such as alcohol remains poorly understood.
Uigi Min, Jihyun Kim, Jinwook Kim, Hyunmi Jin, Hyunji Oh, Soyeon Ahn, Hyeonseok Shin, Wonhee Lee   +7 more
doaj   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial

Scientific Reports, 2017
Short-chain fatty acids (SCFA), formed by microbial fermentation, are believed to be involved in the aetiology of obesity and diabetes. This study investigated the effects of colonic administration of physiologically relevant SCFA mixtures on human ...
Emanuel E. Canfora, Christina M. van der Beek, Johan W. E. Jocken, Gijs H. Goossens, Jens J. Holst, Steven W. M. Olde Damink, Kaatje Lenaerts, Cornelis H. C. Dejong, Ellen E. Blaak   +8 more
doaj   +1 more source

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou, Panagiotis Sardellis, Josip Plascevic, Ribeya Awaes‐Mahmood, Justyna Kaczmarek, Daniel Black Boada, Rosa Thuemmler, Sam Philip   +7 more
wiley   +1 more source