Results 301 to 310 of about 3,763,244 (397)

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Optimizing neurosurgical operating room schedule: Integrating machine learning models for operative time prediction and schedule design. [PDF]

Surg Neurol Int
Nathani KR, Machlab LA, von Kentzinsky HL, Feng E, Jayasuriya NM, Nathani AM, Ibrahim S, Bhandarkar A, Timm PC, Ali R, Tawk RG, Freedman B, Bydon M.   +12 more
europepmc   +1 more source

Predicting MammaPrint Recurrence Risk from Breast Cancer Pathological Images Using a Weakly Supervised Transformer

Advanced Science, EarlyView.
This study presents CPMP, a weakly supervised transformer model that predicts MammaPrint recurrence risk directly from routine histopathological images of early‐stage HR+/HER2− breast cancer patients. CPMP enables spatial heatmap visualization, analysis of cellular‐level interaction patterns, and an in‐depth characterization of morphological phenotypes
Chaoyang Yan, Linwei Li, Xiaolong Qian, Yang Ou, Zhidong Huang, Zhihan Ruan, Wenting Xiang, Hong Liu, Jian Liu   +8 more
wiley   +1 more source

Demographic and Clinical Characteristics of Patients Vaccinated Against Herpes Zoster in a Primary Care Setting in Spain: A Retrospective Study. [PDF]

Vaccines (Basel)
Blanc-Rodriguez-Arias JM, Jimeno-Sanz I, Hernández-Barrera V, Álvaro-Meca A, Torres-Ramos M, Gil-de-Miguel Á.   +5 more
europepmc   +1 more source

Hybrid resource scheduling for aggregation in massive machine-type communication networks

, 2019
Onel L. Alcaraz López, Hirley Alves, Pedro H. J. Nardelli, Matti Latva‐aho   +3 more
openalex   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Further assessment of a model of changeover behavior: Implications for the matching law. [PDF]

J Exp Anal Behav
Avellaneda MA, Shahan TA.
europepmc   +1 more source

Reprogramming Tumor‐Associated Macrophages via Targeted NAT10 Inhibition to Enhance Colorectal Cancer Immunotherapy

Advanced Science, EarlyView.
This study presents the sono‐sensitive nanorobot Sono@NAT10, which targets NAT10 condensates to reprogram tumor‐associated macrophages in colorectal cancer. By reducing the acetylation level of SRSF2 protein and activating HDAC10, Sono@NAT10 promotes M1 polarization, suppresses tumor progression, and strengthens immunotherapy. The approach demonstrates
Jiahao Zhu, Benjie Xu, Rui Hu, Bo Yang, Peipei Shen, Yu Xu, Xiaojun Zhang, Danqi Qian, Gang Wu, Shengjun Ji, Yutian Zhao, Ke Gu   +11 more
wiley   +1 more source

Boosting the influenza vaccine schedule in children with cancer: a prospective open-label study. [PDF]

NPJ Vaccines
Chiu SK, Furlong E, McKinnon EJ, Fox A, Ovando SS, Carolan L, McLean-Tooke A, Oommen J, Yeoh DK, Cheung LC, Gottardo NG, Kotecha RS.   +11 more
europepmc   +1 more source

Lifestyle Medicine Core Competencies: 2025 Update. [PDF]

Am J Lifestyle Med
Rea BL, Cheema S, Lanza S, Makinde MT, Matthews S, Palma M, Szentgyörgyi B, Karlsen MC.   +7 more
europepmc   +1 more source