Results 91 to 100 of about 491,574 (256)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Railway scheduling reduces the expected project makespan. [PDF]
The Critical Chain Scheduling and Buffer Management (CC/BM) methodology, proposed by Goldratt (1997), introduced the concepts of feeding buffers, project buffers and resource buffers as well as the roadrunner mentality.
Demeulemeester, Erik, Tian, Wendi
core
Efficient Work Team Scheduling: Using Psychological Models of Knowledge Retention to Improve Code Writing Efficiency [PDF]
Journal of Systemics, Cybernetics and Informatics, 2014 Development teams and programmers must retain critical information about their work during work intervals and gaps in order to improve future performance when work resumes.
Michael J. Pelosi +3 more
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
SystemsProject Managers face many difficulties when scheduling the development and production of multiple, largely independent systems required for a new capability, especially when there are multiple stakeholders, uncertainties in the expected development time,
Cesare Guariniello, Daniel DeLaurentis
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The impact of predictive inaccuracies on execution scheduling [PDF]
, 2004 This paper investigates the underlying impact of predictive inaccuracies on execution scheduling, with particular reference to execution time predictions. This study is conducted from two perspectives: from that of job selection and from that of resource
Nudd, G. R. +9 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
International Journal of Digital EarthWith the rise of low-cost launches, miniaturized space technology, and commercialization, the cost of space missions has dropped, leading to a surge in flexible Earth observation satellites.
He Wang +6 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source