Results 151 to 160 of about 1,231,038 (365)
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa+13 more
wiley +1 more source
Competitive Algorithms from Competitive Equilibria: Non-Clairvoyant Scheduling under Polyhedral Constraints [PDF]
We introduce and study a general scheduling problem that we term the Packing Scheduling problem. In this problem, jobs can have different arrival times and sizes; a scheduler can process job $j$ at rate $x_j$, subject to arbitrary packing constraints over the set of rates ($\vec{x}$) of the outstanding jobs.
arxiv
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu+7 more
wiley +1 more source
Construction Scheduling and Stability of the Resulting Schedules
Abstract The paper present the concept of stability assessing the of solutions which are construction schedules. Rank have been obtained through the use of task scheduling rules and the application of the KASS software. The aim of the work is the choice of the equivalent solution in terms of the total time of the project.
openaire +3 more sources
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Revisiting the Schedule Graph Generation for the Exact and Sustainable Analysis of Non-preemptive Scheduling [PDF]
This paper addresses the problem of scheduling non-preemptive tasks with release jitter and execution time variation on a uniprocessor. We show that the schedulability analysis based on schedule graph generation, proposed by Nasri and Brandenburg [RTSS 2017], produces negative results when it could be easily avoided by slightly reformalizing the notion
arxiv
A CONJUNCTIVE SCHEDULE OF REINFORCEMENT1 [PDF]
R. J. Herrnstein, W. H. Morse
openalex +1 more source
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
THE EFFECT OF SECOBARBITAL ON A MULTIPLE SCHEDULE IN THE MONKEY [PDF]
Thom Verhave
openalex +1 more source