Results 91 to 100 of about 2,100,013 (302)

CONTRIBUTIONS TO MULTI-AGENT SYSTEMS IMPLEMENTATION FOR PROJECT SCHEDULING [PDF]

open access: yes
Increasing project complexity makes scheduling problems more difficult to solve and requires more versatile algorithms. Two different approaches for the project scheduling optimization could be considered: TCPSP (Time-Constrained Project Scheduling), and
Ileana Ruxandra BADEA   +1 more
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A solution approach for dynamic vehicle and crew scheduling [PDF]

open access: yes
In this paper, we discuss the dynamic vehicle and crew schedulingproblem and we propose a solution approach consisting of solving asequence of optimization problems.
Wagelmans, A.P.M., Huisman, D.
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Constraint Centric Scheduling Guide [PDF]

open access: yes, 2013
The advent of architectures with software-exposed resources (Spatial Architectures) has created a demand for universally applicable scheduling techniques.
Estan, Cristian   +4 more
core  

Optimization Models for Scheduling of Jobs

open access: yesJournal of Research of the National Institute of Standards and Technology, 2006
This work is motivated by a particular scheduling problem that is faced by logistics centers that perform aircraft maintenance and modification. Here we concentrate on a single facility (hangar) which is equipped with several work stations (bays). Specifically, a number of jobs have already been scheduled for processing at the facility; the starting ...
Indika, S. H. Sathish, Shier, Douglas R.
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Phase transitions in project scheduling. [PDF]

open access: yes
The analysis of the complexity of combinatorial optimization problems has led to the distinction between problems which are solvable in a polynomially bounded amount of time (classified in P) and problems which are not (classified in NP).
De Reyck, B, Herroelen, Willy
core  

A mixed integer optimization strategy for oil and gas production planning [PDF]

open access: yes, 2008
Oil and gas production is the cornerstone of the modern petrochemical industry, and its upstream as well as downstream processing provides many challenges to the process modeling, optimization and control areas.
Pistikopoulos, Efstratios N.   +1 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

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