Results 111 to 120 of about 32,083 (265)

Bi-objective bus scheduling optimization with passenger perception in mind. [PDF]

Sci Rep, 2023
Liu S, Liu L, Pei D, Wang J.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Order scheduling optimization in manufacturing enterprises based on MDP and dynamic programming. [PDF]

Sci Rep, 2023
Wulan Q.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Multi-objective scheduling optimization for manufacturing workshop using an adjacency matrix-genetic algorithm

四川大学学报. 自然科学版
Aiming at the multi-objective optimization problem of manufacturing workshop scheduling， a workshop scheduling model is constructed， and a novel multi-objective optimization method for workshop resource scheduling based on the Adjacency Matrix-Genetic ...
DONG Hongliang, FU Fangwenchang
doaj  

Dual Priority Scheduling is Not Optimal.

, 2019
In dual priority scheduling, periodic tasks are executed in a fixed-priority manner, but each job has two phases with different priorities. The second phase is entered after a fixed amount of time has passed since the release of the job, at which point the job changes its priority.
openaire   +4 more sources

Retracted: Production Scheduling Optimization of Garment Intelligent Manufacturing System Based on Big Data. [PDF]

Comput Intell Neurosci, 2023
Intelligence And Neuroscience C.
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Design and Application of Vague Set Theory and Adaptive Grid Particle Swarm Optimization Algorithm in Resource Scheduling Optimization. [PDF]

J Grid Comput, 2023
Han Y, Han P, Yuan B, Zhang Z, Liu L, Panneerselvam J.   +5 more
europepmc   +1 more source