Results 71 to 80 of about 275,856 (278)

Feedback and time are essential for the optimal control of computing systems [PDF]

, 2015
The performance, reliability, cost, size and energy usage of computing systems can be improved by one or more orders of magnitude by the systematic use of modern control and optimization methods.
Kerrigan, EC
core   +2 more sources

Optimal deadline scheduling with commitment [PDF]

2011 49th Annual Allerton Conference on Communication, Control, and Computing (Allerton), 2011
We consider an online preemptive scheduling problem where jobs with deadlines arrive sporadically. A commitment requirement is imposed such that the scheduler has to either accept or decline a job immediately upon arrival. The scheduler's decision to accept an arriving job constitutes a contract with the customer; if the accepted job is not completed ...
Chen, Shiyao, Tong, Lang, He, Ting
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Optimal Multiuser Scheduling Schemes for Simultaneous Wireless Information and Power Transfer

, 2015
In this paper, we study the downlink multiuser scheduling problem for systems with simultaneous wireless information and power transfer (SWIPT). We design optimal scheduling algorithms that maximize the long-term average system throughput under different
Chynonova, Maryna, Morsi, Rania, Ng, Derrick Wing Kwan, Schober, Robert   +3 more
core   +1 more source

Optimal Scheduling for OFDMA Systems [PDF]

2006 Fortieth Asilomar Conference on Signals, Systems and Computers, 2006
We consider a scheduling and resource allocation problem for the downlink of an OFDMA-based wireless network, where the channel estimation error is modeled by a self-noise term in the decoding process. During each time-slot this involves selecting a subset of users for transmission, determining the assignment of available subcarriers to selected users,
Agrawal, Rajeev, Berry, Randall, Huang, Jianwei, Subramanian, Vijay G.   +3 more
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A low-carbon optimization scheduling method of CIES based on PPO algorithm

电力工程技术
The tiered carbon trading mechanism and optimization scheduling model solving algorithm are pivotal for the community integrated energy system (CIES).
CHEN Fan, WU Lingxiao, WANG Man, LYU Ganyun, ZHANG Xiaolian   +4 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source