Results 81 to 90 of about 10,787,486 (301)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2012 Generally speaking, scheduling is the procedure of mapping a set of tasks or jobs (studied objects) to a set of target resources efficiently. More specifically, as a part of a larger planning and scheduling process, production scheduling is essential for
core +1 more source
Co-evolutionary Genetic Algorithms for Reactive Scheduling
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010 Previous researches provided a reactive scheduling method using a genetic algorithm to improve disturbed production schedules, due to unexpected disruptions, such as delays of manufacturing operations.
Yoshitaka TANIMIZU +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Optimal production scheduling for dairy industries [PDF]
, 2005 In this work, a complete two-level framework for use in food and in particular dairy industries is proposed. The specific characteristics of the dairy industry have been taken into consideration, in terms of the behavior of food sales over time and the ...
Patrinos, Panagiotis +3 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Solving two production scheduling problems with sequence-dependent set-up times [PDF]
In today s competitive markets, the importance of good scheduling strategies in manufacturing companies lead to the need of developing efficient methods to solve complex scheduling problems.
Helena Ramalhinho-Lourenço +1 more
core
ÖĞRENME ETKİLİ HAZIRLIK VE TAŞIMA ZAMANLI PARALEL MAKİNELİ ÇİZELGELEME PROBLEMİ
Havacılık ve Uzay Teknolojileri Dergisi, 2006 In studies on scheduling problems, generally setup times and removal times of jobs have been neglected or by including those into processing times solution approaches have been developed.
Tamer Eren , Ertan Güner
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Scheduling uncertain orders in the customer–subcontractor context [PDF]
, 2003 Within the customer–subcontractor negotiation process, the first problem of the subcontractor is to provide the customer with a reliable order lead-time although his workload is partially uncertain.
Grabot, Bernard +2 more
core +1 more source