Results 81 to 90 of about 241,676 (345)

Aerospace Manufacturing Industry: A Simulation-Based Decision Support Framework for the Scheduling of Complex Hoist Lines [PDF]

, 2017
The hoist scheduling problem is a critical issue in the design and control of Automated Manufacturing Systems. To deal with the major complexities appearing in such problem, this work introduces an advanced simulation model to represent the short-term ...
Basán, Natalia Paola, Coccola, Mariana Evangelina, Mendez, Carlos Alberto, Pulido, Raul   +3 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The challenge of integrating non-continuous processes-milk powder plant case study [PDF]

, 2009
The integration of non-continuous processes such as a milk powder plant present a challenge for existing process integration techniques. Current techniques are generally based on steady and continuous operation which for some industries is not the case ...
Atkins, Martin John, Neale, James R., Walmsley, Michael R.W.   +2 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Multi-Agent System Interaction in Integrated SCM\ud [PDF]

, 2009
Coordination between organizations on strategic, tactical and operation levels leads to more effective and efficient supply chains. Supply chain management is increasing day by day in modern enterprises..
Purohit, G. N., Sindhu, Ritu, Wahid, Abdul   +2 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

A Hybrid Metaheuristic Approach for Minimizing the Total Flow Time in A Flow Shop Sequence Dependent Group Scheduling Problem

Algorithms, 2014
Production processes in Cellular Manufacturing Systems (CMS) often involve groups of parts sharing the same technological requirements in terms of tooling and setup. The issue of scheduling such parts through a flow-shop production layout is known as the
Antonio Costa, Fulvio Antonio Cappadonna, Sergio Fichera   +2 more
doaj   +1 more source

Abandoned project restoration model (APRM) for residential construction projects [PDF]

, 2017
Incompletion of construction projects is a common phenomenon in Malaysia. Project abandonment has given an adverse consequences to the economy, society and environment. In the best interest of the end users and other parties involved in the contract, the
Doraisamy, Sanitha V.
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Graph reinforcement learning-driven source-load cooperative scheduling optimization for textile production

Digital Engineering
There are engineering issues caused by the traditional energy scheduling model where the energy generation (source) adjusts according to the energy consumption (load) in textile industrial parks, leading to a disconnect between the energy system and the ...
Tianhao Tan, Tao Wu, Jie Li, Yuyuan Lan, Jinsong Bao   +4 more
doaj   +1 more source