Results 91 to 100 of about 10,787,486 (301)

The Optimization of Flow Shop Scheduling in Milling Stoper Production Using Campbell Dudek Smith Algorithm

Journal of Industrial Engineering and Halal Industries
Non-optimal production scheduling in a flow shop system can increase makespan, idle time, and workload imbalance among machines. This study aims to optimize the production scheduling of a milling stopper in a manufacturing workshop using the CDS ...
Haposan Vincentius Manalu, Insan Kamil, Oki Setiawan, Darti Purnama Sari, Siti Adriani, Ifti Luthviana Dewi, Robi Kurniawan, Lavita Indriani Br. Ginting, Khollilah Nuraini   +8 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Production scheduling in the process industry

, 2013
The purpose of this paper is to formulate an optimization model for the production scheduling problem at continuous production sites. The production scheduling activity should produce a monthly schedule that accounts for orders and forecasts of all products.
Lindholm, Anna, Giselsson, Pontus, Quttineh, Nils-Hassan, Lidestam, Helene, Johnsson, Charlotta, Forsman, Krister   +5 more
openaire   +1 more source

Multi-Product Production Scheduling in Automated Continuous Processes

Bulletin of JSME, 1975
In the multi-product production of coating and heat treatment, various kinds of jigs and fixtures are used exclusively for each product. As the daily fluctuation of delivery requirements is large, either the number of jigs and fixtures maintained or the amount of inventories, has to be kept large.
openaire   +2 more sources

Stability of the optimal schedule for perishable product processing

E3S Web of Conferences, 2023
In linear programming tasks, the optimal solution can remain the same even with a significant deviation of the initial data. Thus, when studying various problems in economic and mathematical analysis, the question of the optimal solution stability often arises.
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A branch-and-bound algorithm for stable scheduling in single-machine production systems. [PDF]

Robust scheduling aims at the construction of a schedule that is protected against uncertain events. A stable schedule is a robust schedule that will change little when variations in the input parameters arise.
Herroelen, Willy, Leus, Roel
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Simulating operational control of production in lumber house building businesses

MATEC Web of Conferences, 2017
Substantial reserves for higher operation efficiency in wooden house building businesses exist in improvements of production control system through methods of simulation and optimization.
Korolchenko Dmitriy, Pizhurin Andrey
doaj   +1 more source