Results 111 to 120 of about 241,676 (345)

Scheduling Coordination in a Supply Chain Using Advance Demand Information. [PDF]

open access: yes
In an environment of mass customization where demand information can be placed in advance with sequencing orders, the question of the best use of this information arises in a supply chain.
Giard, Vincent, Mendy-Bilek, Gisèle
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

An improved cell controller for the aerospace manufacturing [PDF]

open access: yes, 2013
The aerospace manufacturing industry is unique in that production typically focuses on high variety and quality but low volume. Existing flexible manufacturing cells are limited to certain types of machines, robots and cells which makes it difficult to ...
Asif, Seemal, Webb, Philip
core  

Multi-Product Production Scheduling in Automated Continuous Processes

open access: yesBulletin of JSME, 1975
In the multi-product production of coating and heat treatment, various kinds of jigs and fixtures are used exclusively for each product. As the daily fluctuation of delivery requirements is large, either the number of jigs and fixtures maintained or the amount of inventories, has to be kept large.
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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