Results 121 to 130 of about 241,676 (345)
Simulating operational control of production in lumber house building businesses
MATEC Web of Conferences, 2017 Substantial reserves for higher operation efficiency in wooden house building businesses exist in improvements of production control system through methods of simulation and optimization.
Korolchenko Dmitriy, Pizhurin Andrey
doaj +1 more source
The balance of autonomous and centralized control in scheduling problems
Applied Network Science, 2018 The scheduling of processes in a network is a core logistic challenge with a multitude of applications in our complex industrialized world. Often, scheduling decisions are based on incomplete and unreliable information.
Henning Blunck +3 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Theory of constraints (TOC) production and manufacturing performance [PDF]
, 2016 This paper is based on an empirical study of the relationship between Theory of Constraints (TOC) production and operational performance in manufacturing plants.
Panizzolo, Roberto
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Power of pre-processing: production scheduling with variable energy pricing and power-saving states [PDF]
, 2020 Ondřej Benedikt +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Lean implementation to improve scheduling for a multi-cell manufacturing facility [PDF]
, 2009 Includes bibliographical ...
Skelley, Kyle
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source