Results 131 to 140 of about 241,676 (345)

Resource and Application Models for Advanced Grid Schedulers [PDF]

open access: yes, 2003
As Grid computing is becoming an inevitable future, managing, scheduling and monitoring dynamic, heterogeneous resources will present new challenges. Solutions will have to be agile and adaptive, support self-organization and autonomous management, while
Lazarevic, A., Sacks, L.
core  

Impact of Problems Associated with Scheduling and Capacity Planning of a Production Process – An Overview

open access: diamond, 2021
A. Afolalu Sunday   +6 more
openalex   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Global supply chains of high value low volume products [PDF]

open access: yes, 2007
Imperial Users ...
De Sousa, Rui Pedro Domingos Tavares   +1 more
core  

Solving the problem of scheduling the production process based on heuristic algorithms [PDF]

open access: diamond, 2022
Dagmara Łapczyńska   +3 more
openalex   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

A distributed knowledge-based approach to flexible automation : the contract-net framework [PDF]

open access: yes, 1987
Includes bibliographical references (p. 26-29)
Shaw, Michael, 1956-   +1 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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