Results 51 to 60 of about 19,773 (260)

Research on Optimal Power Generation Scheduling for Reservoir in Multi-Tailed River Channels

open access: yesRenmin Zhujiang
To enhance the power generation efficiency of Gezhen Reservoir, the unique engineering layout of hydroelectric generating sets of Gezhen Reservoir in multi-tailed river channels was studied.
ZHANG Yonghui   +4 more
doaj   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Coordinated Scheduling of Automated Loading Platforms in Commercial Logistics

open access: yesJournal of Advanced Transportation
Automated warehousing and distribution has been an innovation approach to reduce costs and increase efficiency in logistics industry. Taking the intelligent demonstration warehouse in a commercial logistics park in Shandong, China as the background, this
Xiaoqian Nie   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Bus crew scheduling using mathematical programming [PDF]

open access: yes, 1986
This thesis describes a bus crew scheduling system, IMPACS, which has been demonstrated to be successful for a wide variety of scheduling conditions, and is at present in regular use by three British bus companies including the largest, London Buses Ltd.
Smith, Barbara Mary
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Rule-based scheduling of air conditioning using occupancy forecasting

open access: yesEnergy and AI, 2020
Heating, ventilation and air conditioning systems represent considerable potential for energy savings, which can be realized through intelligent occupancy-centered control strategies.
Marina Dorokhova   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A GA-based technique for the scheduling of storage tanks

open access: yes, 1999
YesThis paper proposes the application of a genetic algorithm based methodology for the scheduling of storage tanks. The proposed approach is an integration of GA and heuristic rule-based techniques, which decomposes the complex mixed integer ...
Dahal, Keshav P.   +3 more
core   +1 more source

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