Results 61 to 70 of about 19,773 (260)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A novel class of scheduling policies for the stochastic resource-constrained project scheduling problem. [PDF]

open access: yes
We study the resource-constrained project scheduling problem with stochastic activity durations. We introduce a new class of scheduling policies for this problem, which make a number of a-priori sequencing decisions in a pre-processing phase, while the ...
Leus, Roel   +2 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Heuristic procedures for reactive project scheduling. [PDF]

open access: yes
This paper describes new heuristic reactive project scheduling procedures that may be used to repair resource-constrained roject baseline schedules that suer from multiple activity duration disruptions during project execution.The objective is to ...
Van de Vonder, S   +3 more
core  

Marginal productivity index policies for scheduling a multiclass delay-/loss-sensitive queue [PDF]

open access: yes, 2005
We address the problem of scheduling a multiclass M/M/1 queue with a finite dedicated buffer for each class. Some classes are delay-sensitive, modeling real-time traffic (e.g.
Niño-Mora, José   +2 more
core  

Design of an Improved Method for Task Scheduling Using Proximal Policy Optimization and Graph Neural Networks

open access: yesIEEE Access
Modern computational environments have been getting more and more complex and dynamic; hence, mechanisms of task scheduling are increasingly sophisticated in order to guarantee optimal resource usage and reduced latency.
Nemilidinea Anantharami Reddy   +1 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

'The application of Bayesian Optimization and Classifier Systems in Nurse Scheduling' [PDF]

open access: yes, 2004
. Two ideas taken from Bayesian optimization and classifier systems are presented for personnel scheduling based on choosing a suitable scheduling rule from a set for each person's assignment.
Aickelin, Uwe   +5 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Solving two production scheduling problems with sequence-dependent set-up times [PDF]

open access: yes
In today s competitive markets, the importance of good scheduling strategies in manufacturing companies lead to the need of developing efficient methods to solve complex scheduling problems.
Helena Ramalhinho-Lourenço   +1 more
core  

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