Results 61 to 70 of about 3,088,335 (262)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Research on steady-state simulation in dynamic job shop scheduling problem

open access: yesAdvances in Mechanical Engineering, 2015
A systematic research of steady state for the dynamic job shop scheduling problem with jobs releasing continuously over time has been conducted in this article.
Hegen Xiong   +3 more
doaj   +1 more source

A Comparison of Reinforcement Learning Algorithms in Fairness-Oriented OFDMA Schedulers

open access: yesInformation, 2019
Due to large-scale control problems in 5G access networks, the complexity of radio resource management is expected to increase significantly. Reinforcement learning is seen as a promising solution that can enable intelligent decision-making and reduce ...
Ioan-Sorin Comșa   +5 more
doaj   +1 more source

Research on dyeing workshop scheduling methods for knitted fabric production based on a multi-objective hybrid genetic algorithm

open access: yesMeasurement + Control, 2020
As the most important core process in the dyeing and finishing workshop of knitting companies, the dyeing process has the characteristics of multi-variety, small-batch, parallel machine processing of multiple types, and high cost in equipment cleaning ...
Yaqin Zhou   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A Novel Scheduling Index Rule Proposal for QoE Maximization in Wireless Networks

open access: yesAbstract and Applied Analysis, 2014
This paper deals with the resource allocation problem aimed at maximizing users’ perception of quality in wireless channels with time-varying capacity. First of all, we model the subjective quality-aware scheduling problem in the framework of Markovian ...
Ianire Taboada, Fidel Liberal
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Simulation model for resource-constrained construction project

open access: yesOpen Engineering, 2019
Repetition of the same processes on different objects or units of a construction project and their concurrent execution makes it necessary to use the same limited resources at the same time.
Biruk Sławomir, Rzepecki Łukasz
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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