Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Supramolecular Diversity, Theoretical Investigation and Antibacterial Activity of Cu, Co and Cd Complexes Based on the Tridentate N,N,O-Schiff Base Ligand Formed In Situ. [PDF]
Molecules, 2022 Buvaylo EA +5 more
europepmc +1 more source
Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries
British Journal of Pharmacology, EarlyView.Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley +1 more source
Ibn Al-Haitham Journal for Pure and Applied SciencesIn this study, transition complexes of Fe(III), Zn(II), La(III), Ce(III), and Pr(III) with a Schiff base ligand (L), which is derived from 3-hydroxybenzaldehyde and sulfamethoxazole, as the primary ligand, and L-Leucinate as a secondary ligand.
Maysam Basem Abdulsalam +2 more
doaj +1 more source
Metal catalyzed rearrangement of a 2,2'-bipyridine Schiff-base ligand to a quaterpyridine-type complex [PDF]
, 2007 Champouret +21 more
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Cell Proliferation, EarlyView.Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang +10 more
wiley +1 more source
Synthesis and Spectroscopic Investigations of Schiff Base Ligand and Its Bimetallic Ag(I) Complex as DNA and BSA Binders. [PDF]
Biomolecules, 2021 Szymańska M +6 more
europepmc +1 more source
Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies
ChemBioChem, Volume 27, Issue 9, 14 May 2026.This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci +5 more
wiley +1 more source
NiII mol-ecular complex with a tetra-dentate amino-guanidine-derived Schiff base ligand: structural, spectroscopic and electrochemical studies and photoelectric response. [PDF]
Acta Crystallogr E Crystallogr Commun, 2022 Vassilyeva OY +5 more
europepmc +1 more source
Multielectron Redox Chemistry of Transition Metal Complexes Supported by a Non‐Innocent N3P2 Ligand: Synthesis, Characterization, and Catalytic Properties [PDF]
, 2018 A new redox‐active, diarylamido‐based ligand (LN3P2) capable of κ5‐N,N,N,P,P chelation has been used to prepare a series of complexes with the general formula [MII(LN3P2)]X, where M = Fe (1; X = OTf), Co (2; X = ClO4), or Ni (3; X = ClO4).
Ekanayake, Danushka M. +4 more
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