Results 161 to 170 of about 4,462,665 (297)

Synthesis, characterization and antibacterial properties of N,N’-Bis(4-dimethylaminobenzylidene)benzene-1,3-diamine as new Schiff base ligand and its binuclear Zn(II), Cd(II) complexes

open access: yes, 2019
We synthesized a new Schiff base ligand by condensation reaction of 4-dimethylaminobenzaldehyde and 1,3-phenylenediamine. Treatment of this Schiff base ligand with Zinc(II) nitrate and Cadmium(II) nitrate in ethanol medium afforded the corresponding ...
Pakdaman-Azari, Mohammadreza   +2 more
core  

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo   +4 more
wiley   +1 more source

Optimal‐Control 19F PROJECT Improves the Reliability of CPMG‐Derived Relaxation Rates

open access: yesMagnetic Resonance in Chemistry, EarlyView.
PROJECT with seedless optimal control pulses for 19F‐based protein‐ligand interaction screenings allows for a lower error in R2 estimates than those obtained with CPMG for J‐coupled fluorine signals and is indistinguishable from CPMG when the coupling is negligible, at the price of a modest reduction in SNR.
Marco Schiavina   +2 more
wiley   +1 more source

Tailored for Binding: Alanine‐Modified Poly(1‐Naphthylamine) Targets Serum Albumins

open access: yesPolymer Engineering &Science, EarlyView.
Alanine modified poly(1‐naphthylamine). ABSTRACT This study presents a new approach for modifying the structural and functional properties of poly(1‐naphthylamine) (PNA) by incorporating the amino acid alanine (Ala) in different molar proportions (80/20, 50/50, and 20/80 for PNA/Ala) through an ultrasound‐assisted polymerization process.
Nuzhat Nabi, Ufana Riaz
wiley   +1 more source

Rheological and Mechanical Assessment of Injectable Hydrogels: A Framework for Structure–Property Analysis

open access: yesPolymer Engineering &Science, EarlyView.
A rheological and mechanical assessment framework to construct structure‐property‐application relationships for injectable hydrogels. ABSTRACT Injectable hydrogels have attracted massive research attention thanks to their potential biomedical applications.
Hai Xin   +2 more
wiley   +1 more source

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