Results 241 to 250 of about 4,462,665 (297)

Characterization of Full‐Length Antibody Complexes Through HDX‐Mass Spectrometry Coupled With NMR Spectroscopy: New Insight Into Avelumab/PD‐L1 Interaction

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Combining HDX‐MS and NMR enables the mapping of epitopes and paratopes in full‐length antibody complexes, revealing transient interactions and potential artifacts. ABSTRACT Recombinant biomacromolecules have significantly transformed pharmaceuticals, in particular monoclonal antibodies (mAbs) that target key areas in oncology, immunology, inflammation,
Francesca Sacco, Fabio Baroni, Angela Capolupo, Sofia Petrocchi, Jonathan Zöller, Linda Cerofolini, Pasquale Russomanno, Rebecca Calamandrei, Bianca Susini, Siyu Lin, Fabio D'Amici, Enrico Ravera, Julian Langer, Marco Fragai   +13 more
wiley   +2 more sources

Performance Optimization and Prospects of Double Network Hydrogels for Flexible Electronic Devices

ChemElectroChem, Volume 13, Issue 20, 16 October 2026.
This review provides a comprehensive overview of DN hydrogels, focusing on their classification, key properties, and diverse applications. Based on crosslinking mechanisms, DN hydrogels are categorized into chemically crosslinked, physically crosslinked, and hybrid crosslinked systems, each offering distinct advantages in stability, reversibility, and ...
Liu Xing, Feng Ailing, Peng Yue, Guo Yating, Liu Yuhui, Li Lanfen, Zu Yanqing, Liu Peitao, Li Xiaodong   +8 more
wiley   +1 more source

Activating Triplet Excitons in COFs via Layer‐Bridging Co Single Atoms for Photocatalytic H2O2 Production and Tandem C─N Coupling

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
This work demonstrates a layer‐bridging coordination strategy of Co single atoms in COFs that promotes the formation and utilization of triplet excited states. The introduction of Co single atoms induces pronounced energy‐level splitting and enhanced spin–orbit coupling, facilitating the generation of 1O2 and O2•– for efficient photocatalytic H2O2 ...
Guoen Tang, Jianjun Zhang, Guijie Liang, Jinfeng Zhang, Chuanbiao Bie, Jiaguo Yu, Hermenegildo García   +6 more
wiley   +2 more sources

4‐Octyl Itaconate Attenuates Age‐Induced Parotid Gland Dysfunction Through the Suppression of Fibrosis and Lipid Deposition by AMPKα/PPARα and the Inhibition of Oxidative Stress via the AMPKα/Nrf2 Signaling Pathway

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
4‐Octyl itaconate (4‐OI) attenuates age‐induced parotid gland dysfunction through the suppression of fibrosis and lipid deposition by AMPKα/PPARα and the inhibition of oxidative stress via the AMPKα/Nrf2 signaling pathway. 4‐OI activates AMPKα, which in turn stimulates both the PPARα and Nrf2 pathways. Activation of PPARα enhances FAO and reduces lipid
Yun Chen, Tianyuan Gong, Zhongyan Shan, Jing Lai, Yiming Xu, Han Zhao, Lilei Zhu   +6 more
wiley   +1 more source

New use of mononuclear Mn/Co/Ni/Cu complexes of symmetric N₂O₂-type Schiff base as hydrogen-evolving catalysts. [PDF]

R Soc Open Sci
Hussein FA, Kumar R, Stein M, Kaur-Ghumaan S.   +3 more
europepmc   +1 more source

Multifunctional Schiff base nanoparticles for environmental remediation: from adsorption to sensing, photocatalysis and antimicrobial applications. [PDF]

RSC Adv
Yadav S, Kamboj A, Yadav A, Poonia K.
europepmc   +1 more source

Evolution of Metal-Based Anticancer Therapeutics: Chemical Foundations, Platinum Drugs, and Emerging Schiff Base Ruthenium(II) and Iridium(III) Complexes. [PDF]

ACS Omega
Joshi B, Shivashankar M.
europepmc   +1 more source

Synthesis, Structural Elucidation, and Anticancer Efficacy Evaluation of a Novel Nd(III)-Schiff Base Complex: Experimental and Computational Insights. [PDF]

Chem Biodivers
Balboul BAA, Taha RH, Alali I, Alhathlaul N, Alsirhani AM, Saleh AM, Yousef TA, Benassi E.   +7 more
europepmc   +1 more source

From oxido-bridged dimers to hydrogen-bonded assemblies: steric control of self-assembly in <i>cis</i>-dioxovanadium(V) Schiff-base complexes.

Dalton Trans
Shepard EJ, Bates AC, Chang CJ, Gibson AM, Miller AR, Arulsamy N, Komarnicka UK, McLauchlan CC, Crans DC.   +8 more
europepmc   +1 more source