Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees [PDF]
The radiation-attenuated Schistosoma mansoni vaccine is highly effective in rodents and primates but has never been tested in humans, primarily for safety reasons.
Abe K.+65 more
core +2 more sources
Intestinal parasitic infections in schoolchildren in different settings of Côte d'Ivoire : effect of diagnostic approach and implications for control [PDF]
BACKGROUND: Social-ecological systems govern parasitic infections in humans. Within the frame of assessing the accuracy of a rapid diagnostic test for Schistosoma mansoni in Cote d'Ivoire, three different endemicity settings had to be identified and ...
AS Stensgaard+49 more
core +3 more sources
Microhabitat preferences of Biomphalaria pfeifferi and Lymnaea natalensis in a natural and a man-made habitat in southeastern Tanzania. [PDF]
Schistosoma mansoni is an important human parasitic disease which is widespread throughout Africa. As Biomphalaria pfeifferi snails act as intermediate host, knowledge of their population ecology is an essential prerequisite towards understanding disease
Tanner, M, Utzinger, J
core +4 more sources
ABSTRACT Background and Aims Schistosomiasis is a neglected tropical disease affecting more than 250 million people worldwide. Eggs of the parasitic helminth S. mansoni cause major morbidity in the liver, spleen and intestine. Of note, egg‐released soluble antigens (SEA) induce the transcription factor c‐Jun in hepatocytes, promoting hepatocellular ...
Frederik Stettler+18 more
wiley +1 more source
Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs [PDF]
Treatment with praziquantel (PZQ) has become virtually the sole basis of schistosomiasis control in sub-Saharan Africa and elsewhere, and the drug is reviewed here in the context of the increasing rate that it is being used for this purpose. Attention is
A. MBAYE+22 more
core +2 more sources
Sigmoid Schistosomiasis Granuloma Manifested as a Large Painless Supra‐Pubic Mass: A Case Report
ABSTRACT Schistosomiasis remains a prevalent parasitic disease in tropical and subtropical regions, ranking second to malaria in terms of parasitic burden. The disease manifests in two primary forms: urinary schistosomiasis, caused by Schistosoma haematobium, and intestinal schistosomiasis, associated with S. mansoni and S. japonicum.
Rawa Badri+5 more
wiley +1 more source
Introduction: The detection of schistosome eggs in stool or urine specimens is the most used technique in population-based studies, while the rectal mucosal biopsy is the commonly used technique in hospital setting.
Kaly Keïta+19 more
doaj +1 more source
Background Accurate identification of schistosome species infecting intermediate host snails is important for understanding parasite transmission, schistosomiasis control and elimination.
Yves-Nathan T. Tian-Bi+15 more
doaj +1 more source
The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza+9 more
wiley +1 more source
The epidemiology of Schistosoma haematobium in Odau community in the Niger Delta area of Nigeria
A study was conducted between August 2001 and July 2002 to investigate the current pattern of prevalence and intensity of Schistosoma haematobium infection at Odau Community in the Niger Delta Area of Nigeria.. Three hundred urine specimens were examined
PI Agi, EJ Okafor
doaj +1 more source