Results 1 to 10 of about 64,678 (294)

Alterations in gut microbiome and metabolite profile of patients with Schistosoma japonicum infection

open access: yesParasites & Vectors, 2023
Background Schistosoma infection is a significant public health issue, affecting over 200 million individuals and threatening 700 million people worldwide. The species prevalent in China is Schistosoma japonicum.
Chen Zhou   +10 more
doaj   +2 more sources

iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats.

open access: yesPLoS Neglected Tropical Diseases, 2022
Humans and a wide range of mammals are generally susceptible to Schistosoma infection, while some rodents such as Rattus rats and Microtus spp are not.
Jia Shen   +6 more
doaj   +2 more sources

Characteristics of Intestinal Flora in Patients With Schistosoma japonicum Infection Undergoing Splenectomy. [PDF]

open access: yesParasite Immunol
ABSTRACT Schistosomiasis japonica is a parasitic disease that seriously endangers human health. Patients with advanced Schistosoma japonicum infection often suffer from cirrhosis and portal hypertension. Splenectomy has been widely used in the treatment of these patients. Previous studies have confirmed that S. japonicum infection is closely related to
Zhou C, Zhang P, Ming Y.
europepmc   +2 more sources

Characterization of the E26H Mutant Schistosoma japonicum Glutathione S-Transferase. [PDF]

open access: yesProteins
ABSTRACT Glutathione‐S‐transferase, such as that of Schistosoma japonicum (sjGST) belongs to the most widely utilized fusion tags in the recombinant protein technology. The E26H mutation of sjGST has already been found to remarkably improve its ability for binding divalent ions, enabling its purification with immobilized metal affinity chromatography ...
Mótyán JA, Veres ÁN, Tőzsér J.
europepmc   +2 more sources

Development of a novel real-time polymerase chain reaction assay for the sensitive detection of Schistosoma japonicum in human stool.

open access: yesPLoS Neglected Tropical Diseases, 2021
BackgroundElimination and control of Schistosoma japonicum, the most virulent of the schistosomiasis-causing blood flukes, requires the development of sensitive and specific diagnostic tools capable of providing an accurate measurement of the infection ...
Sara Halili   +4 more
doaj   +2 more sources

Xiaochaihu decorction relieves liver fibrosis caused by Schistosoma japonicum infection via the HSP47/TGF-β pathway

open access: yesParasites & Vectors, 2020
Background Hepatic fibrosis caused by chronic infection with Schistosoma japonica remains a serious public health problem in the world. Symptoms include inflammation, liver granuloma and fibrosis, whilst treatment options are still limited.
Yuzheng Huang   +6 more
doaj   +2 more sources

Species-specific detection of Schistosoma japonicum using the ‘SNAILS’ DNA-based biosensor [PDF]

open access: yesCommunications Biology
The neglected tropical disease schistosomiasis continues to be a global health concern, especially in low- and middle-income countries, with at least 250 million people infected worldwide and a further 779 million at risk of infection.
Alexander J. Webb   +5 more
doaj   +2 more sources

Schistosoma japonicum extracellular vesicle proteins serve as effective biomarkers for diagnosing parasite infection [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
Schistosoma species are the causative agent of schistosomiasis and shows worldwide distribution. There is a great need to develop a sensitive diagnostic approach for controlling the disease.
Huixin Wu   +6 more
doaj   +2 more sources

Alterations of the Mice Gut Microbiome via Schistosoma japonicum Ova-Induced Granuloma

open access: yesFrontiers in Microbiology, 2019
Schistosomiasis, also called bilharziasis, is a neglected tropical disease induced by Schistosoma spp. that causes hundreds of millions of infections. Although Schistosoma ova-induced granulomas commonly cause inflammation, hyperplasia, ulceration, micro
Yanqing Zhao   +16 more
doaj   +2 more sources

Characterizing genetic variation on the Z chromosome in Schistosoma japonicum reveals host-parasite co-evolution [PDF]

open access: yesParasites & Vectors
Background Schistosomiasis is a neglected tropical disease that afflicts millions of people worldwide; it is caused by Schistosoma, the only dioecious flukes with ZW systems. Schistosoma japonicum is endemic to Asia; the Z chromosome of S.
An Zhou   +7 more
doaj   +2 more sources

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