Results 91 to 100 of about 40,666 (217)

In vivo and in vitro activity of oil extract of garlic (Allium sativum Linnaeus) against Schistosoma japonicum cercariae

Revista da Sociedade Brasileira de Medicina Tropical
: INTRODUCTION: The activity of garlic oil extract against Schistosoma japonicum cercariae was evaluated. METHODS: The in vitro and in vivo cercaricidal activities against S. japonicum larvae were determined. RESULTS: Exposure to ≥ 10-6 (v/v) garlic
Kang Wan, Peng Wang, Leibo Zhang
doaj   +1 more source

Crystal structure of Schistosoma mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state

Acta Crystallographica Section D, Volume 82, Issue 2, Page 140-150, February 2026.
Structural characterization of S. mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state and identifies a schistosome‐specific epitope.Schistosoma mansoni cathepsin D1 (SmCD1) has been shown to be an essential enzyme for helminth metabolism due to its role in haemoglobin degradation: a key amino‐acid ...
Kelly L. Parker, John D. Clarke, Xiaojiao Liu, Barbara F. Gomes, Lauren E.-A. Eyssen, Nicholas Furnham, Floriano Paes Silva-Jr, Raymond J. Owens   +7 more
wiley   +1 more source

Wnt Signaling Pathway: Biological Function, Diseases, and Therapeutic Interventions

MedComm, Volume 7, Issue 1, January 2026.
The Wnt signaling pathway is essential for development and tissue homeostasis, while its dysregulation drives diverse diseases. This review systematically outlines its components, functions, regulators, and preclinical models, highlighting secreted frizzled‐related proteins (SFRPs) as context‐dependent, biphasic modulators.
Xiaoyu Jin, Jiahui Wang, Runyi Cao, Dongsheng Jiang   +3 more
wiley   +1 more source

Gastrointestinal Neoplasia Associated with Bowel Parasitosis: Real or Imaginary?

Journal of Tropical Medicine, 2011
Several parasitic species are well known to have carcinogenic properties, namely; Schistosoma hematobium (squamous cell carcinoma of the bladder) and the liver flukes Opisthorchis and Chlonorchis (cholangiocarcinoma).
Michael R. Peterson, Noel Weidner
doaj   +1 more source

Comparative Study of Transcriptome Profiles of Mouse Livers and Skins Infected by Fork-Tailed or Non-Fork-Tailed Schistosoma japonicum

Frontiers in Microbiology, 2017
Schistosoma japonicum (S. japonicum) is a worldwide spread pathogen which penetrates host skin and then induces several diseases in infected host, such as fibrosis, formation of granulomas, hepatocirrhosis, and hepatomegaly.
Yan Yang, Jun-Jun He, Shuang Hu, Hua Chang, Xun Xiang, Jian-Fa Yang, Feng-Cai Zou   +6 more
doaj   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

The ultrastructural architecture of the adult Schistosoma japonicum tegument

, 2003
The tegument of the adult blood fluke Schistosoma japonicum is in direct contact with the host blood and immune systems. A comprehensive understanding of the ultrastructure of the tegument is crucial to the understanding of how the parasite maintains ...
Gobert, Geoffrey N., Jones, MK, Stenzel, DJ, McManus, DP, McManus, Donald, Gobert, GN, Stenzel, Deborah J., Jones, Malcolm K.   +7 more
core   +1 more source

Alterations of the Mice Gut Microbiome via Schistosoma japonicum Ova-Induced Granuloma

Frontiers in Microbiology, 2019
Schistosomiasis, also called bilharziasis, is a neglected tropical disease induced by Schistosoma spp. that causes hundreds of millions of infections. Although Schistosoma ova-induced granulomas commonly cause inflammation, hyperplasia, ulceration, micro
Yanqing Zhao, Yanqing Zhao, Shuguo Yang, Shuguo Yang, Bei Li, Bei Li, Wei Li, Jue Wang, Jue Wang, Zongyun Chen, Zongyun Chen, Jing Yang, Jing Yang, Huabing Tan, Huabing Tan, Jian Li, Jian Li   +16 more
doaj   +1 more source

A REVIEW OF SCHISTOSOMIASIS IN INDONESIA WITH REFERENCE TO SCHISTOSOMA JAPONICUM

, 2012
Tinjauan tentang Schistosoma di Indonesia ini mencakup Schistosoma japonicum, S. incognitum, S. spindale dan Trichohilharzia brevis. Tinjauan dibuat atas dasar laporan-laporan penelitian yang telah diterbitkan.
Liat, Lim Boo; Institute for Medical Research, Kuala Lumpur, Malaysia, Sudomo, M.; Health Ecology Research Centre, National Institute of Health Research and Development, Jakarta, Indonesia   +1 more
core   +1 more source

Identification and validation of a Schistosoma japonicum U6 promoter

Parasites & Vectors, 2017
Background RNA polymerase III promoters have been widely used to express short hairpin-RNA (shRNA), microRNA (miRNA), and small guide RNA (sgRNA) in gene functional analysis in a variety of organisms including Schistosoma mansoni.
Qing Li, Wan Wang, Nan Zhao, Pengcheng Li, Yue Xin, Wei Hu   +5 more
doaj   +1 more source