Results 101 to 110 of about 51,328 (205)

Schistosoma japonicum peptide SJMHE1 suppresses airway inflammation of allergic asthma in mice

Journal of Cellular and Molecular Medicine, 2019
Helminths and their products can shape immune responses by modulating immune cells, which are dysfunctional in inflammatory diseases such as asthma. We previously identified SJMHE1, a small molecule peptide from the HSP60 protein of Schistosoma japonicum.
Wenzhe Zhang, Li Li, Y. Zheng, F-B Xue, Mengzhu Yu, Yongbin Ma, Liyang Dong, Zirui Shan, Dingqi Feng, Ting Wang, Xuefeng Wang   +10 more
semanticscholar   +1 more source

First case report of Schistosoma japonicum in Nepal

Access Microbiology, 2020
Background. Schistosomiasis, globally, is significant public as well as veterinary health problem as it is associated with a wide range of clinical conditions in humans and animals. Schistosomiasis is mostly caused by the following species of genus Schistosoma: Schistosoma japonicum, Schistosoma haematobium, Schistosoma mekongi ...
Dipendra Bajracharya, Sanjeet Pandit, Durga Bhandari   +2 more
openaire   +3 more sources

Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection

Cells, 2019
Background: Schistosomiasis is an immunopathogenic disease in which Th17 cells play vital roles. Hepatic granuloma formation and subsequent fibrosis are its main pathologic manifestations and the leading causes of hepatic cirrhosis, and effective ...
W. Zhou, Yingying Yang, C. Mei, Panpan Dong, S. Mu, Hongchu Wu, Yonghua Zhou, Yi Zheng, F. Guo, Jun-Qi Yang   +9 more
semanticscholar   +1 more source

Histopathological Study of Wistar Rat Liver Infected with Schistosoma japonicum

WMJ (Warmadewa Medical Journal)
Schistosoma, including Schistosoma japonicum (S. japonicum), can live with an intermediate host, such as rats, and infect mammals, such as humans and rats. We can use a rat model to understand the pathophysiology of Schistosoma. The aim of this study is
David Pakaya , Varel Bramantio Gagola, Christin Rony Nayoan , Junjun Fitriani , Vera Diana Towidjojo   +4 more
doaj   +1 more source

Parasite-derived circulating microRNAs as biomarkers for the detection of human Schistosoma japonicum infection

Parasitology, 2019
Novel tools for early diagnosis and monitoring of schistosomiasis are urgently needed. This study aimed to validate parasite-derived miRNAs as potential novel biomarkers for the detection of human Schistosoma japonicum infection.
Y. Mu, Pengfei Cai, R. Olveda, Allen G P Ross, David U. Olveda, D. McManus   +5 more
semanticscholar   +1 more source

Therapeutic efficacy of Schistosoma japonicum cystatin on sepsis-induced cardiomyopathy in a mouse model

Parasites & Vectors, 2019
Myocardial dysfunction is one of the most common complications of multiple organ failure in septic shock and significantly increases mortality in patients with sepsis.
Shifang Gao, Huihui Li, H. Xie, Shili Wu, Yuan Yuan, L. Chu, Si Sun, Huijuan Yang, Lingqing Wu, Yongsheng Bai, Qiao-mei Zhou, Xin Wang, B. Zhan, Huafeng Cui, Xiaodi Yang   +14 more
semanticscholar   +1 more source

Expression of TLR2, TLR3, TLR4, and TLR7 on pulmonary lymphocytes of Schistosoma japonicum-infected C57BL/6 mice

Innate Immunity, 2019
Despite the paramount role of TLRs in the induction of innate immune and inflammatory responses, there is a paucity of studies on the role of TLRs in Schistosoma japonicum infection.
Dianhui Chen, Yi Zhao, Yuanfa Feng, Chenxi Jin, Quan Yang, Huaina Qiu, Hongyan Xie, S. Xie, Yi Zhou, Jun Huang   +9 more
semanticscholar   +1 more source

B1 cells protect against Schistosoma japonicum–induced liver inflammation and fibrosis by controlling monocyte infiltration

PLoS Neglected Tropical Diseases, 2019
During Schistosoma infection, lack of B cells results in more severe granulomas, inflammation, and fibrosis in the liver, but the mechanisms underlying this pathology remain unclear.
Liang Yong, Yuanyuan Tang, Cui-ping Ren, Miao Liu, Ji-jia Shen, Xin Hou   +5 more
semanticscholar   +1 more source

Variations in fecal Schistosoma japonicum egg counts.

The American journal of tropical medicine and hygiene, 1998
Variations in fecal Schistosoma japonicum egg counts were studied in ZhuXi administrative village, JiangXi Province, China. Population stool examinations were collected with duplicate, standard, 41.5-mg Kato-Katz thick smears on seven consecutive days for 570 individuals from two natural (individual) villages: village I with high endemicity and village
Yu, J. M., de Vlas, S. J., Yuan, H. C., Gryseels, B.   +3 more
openaire   +5 more sources

Schistosome serine protease inhibitors: parasite defense or homeostasis?

Anais da Academia Brasileira de Ciências, 2011
Serpins are a structurally conserved family of macromolecular inhibitors found in numerous biological systems. The completion and annotation of the genomes of Schistosoma mansoni and Schistosoma japonicum has enabled the identification by phylogenetic ...
Landys A. Lopez Quezada, James H McKerrow   +1 more
doaj   +1 more source