Clonorchis sinensis Crude Antigen Suppresses Osteoclast Differentiation via Modulation of the NF‐κB and MAPK Signaling Pathway. ABSTRACT Background Clonorchis sinensis crude antigen (CsCA) is recognized for its immunomodulatory capacity in host‐pathogen interactions and immune‐related pathologies, its direct impact on bone remodeling cells remains ...
Lili Tang +9 more
wiley +1 more source
Helminths in the gastrointestinal tract 1 as modulators of immunity and pathology [PDF]
Helminth parasites are highly prevalent in many low- and middle-income countries, in which inflammatory bowel disease and other immunopathologies are less frequent than in the developed world.
Fleming, John O. +2 more
core +1 more source
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
Contrasting reservoirs for Schistosoma japonicum between marshland and hilly regions in Anhui, China--a two-year longitudinal parasitological survey. [PDF]
Schistosoma japonicum remains highly endemic in many counties in China and has recently re-emerged, to a large extent, in previously controlled areas. To test the hypothesis that small rodents and less agriculturally important domestic animals such as ...
Donnelly, Christl A +5 more
core +1 more source
Variations in fecal Schistosoma japonicum egg counts.
Variations in fecal Schistosoma japonicum egg counts were studied in ZhuXi administrative village, JiangXi Province, China. Population stool examinations were collected with duplicate, standard, 41.5-mg Kato-Katz thick smears on seven consecutive days for 570 individuals from two natural (individual) villages: village I with high endemicity and village
Yu, J. M. +3 more
openaire +4 more sources
Expression profile of the Schistosoma japonicum degradome reveals differential protease expression patterns and potential anti-schistosomal intervention targets. [PDF]
Blood fluke proteases play pivotal roles in the processes of invasion, nutrition acquisition, immune evasion, and other host-parasite interactions. Hundreds of genes encoding putative proteases have been identified in the recently published schistosome ...
Shuai Liu +7 more
doaj +1 more source
The swine flu alert: keeping Asia safe [PDF]
After years of concern about H5N1 bird flu, the new flu causing global alarm is a pig virus of the H1N1 family. As influenza reports erupt around the world, inevitable questions are arising. Is this the big one?
Balen, J, Caballerho-Anthony, M, Chng, B
core
Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and Eukaryotes
ABSTRACT Lysine acetylation plays a crucial role in cellular processes and is found across various evolutionary organisms. Recent advancements in proteomic techniques revealed the presence of acetylation in thousands of non‐histone proteins. Here, we conducted extensive meta‐analysis of 48 acetylomes spanning diverse organisms, including archaea ...
Bruno Sousa Bonifácio +6 more
wiley +1 more source
Patent Landscape of Helminth Vaccines and Related Technologies [PDF]
Executive Summary This report focuses on patent landscape analysis of technologies related to vaccines targeting parasitic worms, also known as helminths.
Burke, Rayna +4 more
core +1 more source
In recent years, the prevalence and infection intensity of Schistosoma japonicum in endemic areas of the Philippines have significantly decreased due to yearly population-based treatment strategies, yet transmission rates remain high and uninterrupted ...
R. Fornillos +9 more
semanticscholar +1 more source

