Results 11 to 20 of about 64,179 (295)
Functional characterisation of Schistosoma japonicum acetylcholinesterase [PDF]
Parasites & Vectors, 2016 Acetylcholinesterase (AChE) is an important metabolic enzyme of schistosomes present in the musculature and on the surface of the blood stage where it has been implicated in the modulation of glucose scavenging from mammalian host blood. As both a target for the antischistosomal drug metrifonate and as a potential vaccine candidate, AChE has been ...
Malcolm K. Jones +7 more
openaire +8 more sources
Characteristics of Intestinal Flora in Patients With Schistosoma japonicum Infection Undergoing Splenectomy. [PDF]
Parasite ImmunolABSTRACT Schistosomiasis japonica is a parasitic disease that seriously endangers human health. Patients with advanced Schistosoma japonicum infection often suffer from cirrhosis and portal hypertension. Splenectomy has been widely used in the treatment of these patients. Previous studies have confirmed that S. japonicum infection is closely related to
Zhou C, Zhang P, Ming Y.
europepmc +2 more sources
Characterization of the E26H Mutant Schistosoma japonicum Glutathione S-Transferase. [PDF]
ProteinsABSTRACT Glutathione‐S‐transferase, such as that of Schistosoma japonicum (sjGST) belongs to the most widely utilized fusion tags in the recombinant protein technology. The E26H mutation of sjGST has already been found to remarkably improve its ability for binding divalent ions, enabling its purification with immobilized metal affinity chromatography ...
Mótyán JA, Veres ÁN, Tőzsér J.
europepmc +2 more sources
Frontiers in Immunology, 2022 Schistosomiasis caused by Schistosoma japonicum is a serious public health problem in China. Granuloma and hepatic fibrosis are the main pathological features of schistosomiasis japonica. The role and mechanism of egg-derived exosomes of S.
Yiluo Wang +7 more
semanticscholar +1 more source
Journal of Nanobiotechnology, 2022 Background Type 1 diabetes mellitus (T1DM) is an autoimmune disease mediated by autoreactive T cells and dominated by Th1 response polarization. Insulin replacement therapy faces great challenges to this autoimmune disease, requiring highly frequent ...
Haoming Huang +8 more
semanticscholar +1 more source
Pathology and molecular mechanisms of Schistosoma japonicum-associated liver fibrosis
Frontiers in Cellular and Infection Microbiology, 2022 Schistosomiasis has been widely disseminated around the world, and poses a significant threat to human health. Schistosoma eggs and soluble egg antigen (SEA) mediated inflammatory responses promote the formation of egg granulomas and liver fibrosis. With
Zhilong Liu +3 more
semanticscholar +1 more source
Parasites & Vectors, 2022 Background Schistosoma japonicum infection is an important public health problem, imposing heavy social and economic burdens in 78 countries worldwide. However, the mechanism of transition from chronic to advanced S.
Chen Zhou +9 more
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 The microRNA‐124‐3p plays an important role in regulating development and neurogenesis. Previous microRNA sequencing analyses of Schistosoma japonicum revealed sja-miR-124-3p differential expression patterns in schistosomes from different hosts and at ...
Xue Zhou +5 more
semanticscholar +1 more source
Ecological model to predict potential habitats of Oncomelania hupensis, the intermediate host of Schistosoma japonicum in the mountainous regions, China [PDF]
, 2015 Schistosomiasis japonica is a parasitic disease that remains endemic in seven provinces in the People's Republic of China (P.R. China). One of the most important measures in the process of schistosomiasis elimination in P.R.
Liu, Lu +3 more
core +12 more sources
Alteration of the fecal microbiota in Chinese patients with Schistosoma japonicum infection
Parasite, 2021 Schistosoma japonicum infection causes pathological injury to the host. Multiple studies have shown that intestinal helminth infection causes dysbiosis for the gut microbial community and impacts host immunology. However, the effect of acute S. japonicum
Yan-yan Jiang +8 more
semanticscholar +1 more source