Results 31 to 40 of about 20,404 (250)

Xiaochaihu decorction relieves liver fibrosis caused by Schistosoma japonicum infection via the HSP47/TGF-β pathway

Parasites & Vectors, 2020
Background Hepatic fibrosis caused by chronic infection with Schistosoma japonica remains a serious public health problem in the world. Symptoms include inflammation, liver granuloma and fibrosis, whilst treatment options are still limited.
Yuzheng Huang, Jin Lu, Yongliang Xu, Chunrong Xiong, Deshen Tong, Nannan Hu, Haitao Yang   +6 more
doaj   +1 more source

Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa [PDF]

, 2017
Multihost multiparasite systems are evolutionarily and ecologically dynamic, which presents substantial trans‐disciplinary challenges for elucidating their epidemiology and designing appropriate control.
Borlase, A, Rudge, J W, Webster, J P
core   +3 more sources

Analysis and characterization of the genes encoding the Dicer and Argonaute proteins of Schistosoma japonicum

Parasites & Vectors, 2010
Background The Dicer and Argonaute(AGO) proteins within the small RNA regulatory pathways (SRRPs) play an indispensable role in regulation of gene expression.
Sun Jun, Wang Zhangxun, Xue Xiangyang, Luo Rong, Zou Ying, Pan Weiqing   +5 more
doaj   +1 more source

Deficiency of PKCλ/ι alleviates the liver pathologic impairment of Schistosoma japonicum infection by thwarting Th2 response

Parasites & Vectors, 2022
Background The activation of immune response driven by the eggs of Schistosoma japonicum and the subsequent secretions is the culprit behind granulomatous inflammation and liver fibrosis.
Congjin Mei, Yingying Yang, Panpan Dong, Lijun Song, Yonghua Zhou, Yongliang Xu, Chuanxin Yu   +6 more
doaj   +1 more source

The inhibitory effect against collagen-induced arthritis by Schistosoma japonicum infection is infection stage-dependent

BMC Immunology, 2010
Background A long-term existing schistosome infection can aid in maintaining immuno-homeostasis, thus providing protection against various types of autoimmune diseases to the infected host. Such benefits have often been associated with acute or egg stage
Chi FengLi, Li Jun, Chen ChunXia, Yin Lan, Zhuang WenJia, Li Jia, He YunKun, Bai YanShuang, Chen Xiao-Ping   +8 more
doaj   +1 more source

Hepatic stellate cells and parasite-induced liver fibrosis [PDF]

, 2010
: Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Allen, JT, Anthony, BJ, Li, YS, McManus, DP   +3 more
core   +2 more sources

The genetic variation of different developmental stages of Schistosoma japonicum: do the distribution in snails and pairing preference benefit the transmission?

Parasites & Vectors, 2020
Background Schistosoma japonicum is a waterborne parasite that causes schistosomiasis in humans and in more than 40 animal species. Schistosoma japonicum shows distinct genetic differentiation among geographical populations and multiple hosts, but the ...
Meng-Jie Gu, Yan-Wei Li, Aidan M. Emery, Shi-Zhu Li, Yong-Zhong Jiang, Hui-Fen Dong, Qin-Ping Zhao   +6 more
doaj   +1 more source

Frontiers of parasitology research in the People's Republic of China : infection, diagnosis, protection and surveillance [PDF]

, 2012
: Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical modelling, monitoring, evaluation, surveillance and public ...
Bergquist, R., Chen, J. H., Chen, J. X., Tanner, M., Utzinger, J., Wang, H., Zhou, X. N.   +6 more
core   +2 more sources

SjTat-TPI facilitates adaptive T-cell responses and reduces hepatic pathology during Schistosoma japonicum infection in BALB/c mice

Parasites & Vectors, 2015
Background Schistosomiasis is a kind of parasitic zoonoses which causes serious damage to public health and social development. China is one of the countries most affected by Schistosoma japonicum and an effective vaccine is still needed.
Wenyue Zhang, Xiaofeng Luo, Fan Zhang, Yuxiao Zhu, Bingya Yang, Min Hou, Zhipeng Xu, Chuanxin Yu, Yingying Chen, Lin Chen, Minjun Ji   +10 more
doaj   +1 more source

Anti-embryonation immunity in murine schistosomiasis japonica (Philippines)

Memorias do Instituto Oswaldo Cruz, 1995
The hypothesis that granuloma modulation and disease abatement in chronic infection with Schistosoma japonicum could be ascribed to antibody-mediated effects on egg maturation and egg viability, arose from studies performed with mice in the Philippines ...
G. F. Mitchell, E. G. Garcia, K. M. Davern, W. U. Tiu   +3 more
doaj   +1 more source