Salmonella typhimurium Infection Reduces Schistosoma japonicum Worm Burden in Mice
Coinfection of microorganisms is a common phenomenon in humans and animals. In order to further our understanding of the progress of coinfection and the possible interaction between different pathogens, we have built a coinfection mouse model with ...
Xiaoyang Zhu +4 more
doaj +1 more source
Quantitative detection of Schistosoma japonicum cercariae in water by real-time PCR. [PDF]
In China alone, an estimated 30 million people are at risk of schistosomiasis, caused by the Schistosoma japonicum parasite. Disease has re-emerged in several regions that had previously attained transmission control, reinforcing the need for active ...
Yuen Wai Hung, Justin Remais
doaj +1 more source
Hepatic stellate cells and parasite-induced liver fibrosis [PDF]
: Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Allen, JT +3 more
core +2 more sources
Recombinant expression systems: the obstacle to helminth vaccines? [PDF]
A
Claerebout, Edwin +3 more
core +2 more sources
Schistosomiasis is characterized by liver fibrosis, and studies have indicated that Schistosoma japonicum (S. japonicum) eggs can limit the progression of liver fibrosis. However, the detailed molecular mechanisms are yet unclear. Extracellular vesicles (
Lifu Wang +11 more
doaj +1 more source
TLR2 directing PD-L2 expression inhibit T cells response in Schistosoma japonicum infection. [PDF]
Toll-like receptor 2 (TLR2) was shown to be an important immune receptor involved in the recognition of schistosome antigens, especially soluble egg antigen (SEA).
Yanan Gao +6 more
doaj +1 more source
A role for peroxisome proliferator-activated receptors in the immunopathology of schistosomiasis? [PDF]
Peroxisome proliferator-activated receptors (PPARs) have been demonstrated to have a role in immune regulation. In general, they are anti-inflammatory and promote Th2 type responses, and they are associated with the alternative activation of macrophages.
Allen, JT +3 more
core +4 more sources
Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa [PDF]
Multihost multiparasite systems are evolutionarily and ecologically dynamic, which presents substantial trans‐disciplinary challenges for elucidating their epidemiology and designing appropriate control.
Borlase, A, Rudge, J W, Webster, J P
core +4 more sources
Hemolytic factors in Schistosoma japonicum eggs [PDF]
Extracts of Schistosoma japonicum eggs were found to exhibit hemolytic activity on erythrocytes of various species. The hemolytic reaction took place more rapidly at 37 degrees C than at 4 degrees C and did not require divalent cations. The degree of hemolysis was dependent on the concentration of the egg extracts.
H, Asahi +3 more
openaire +2 more sources
Frontiers of parasitology research in the People's Republic of China : infection, diagnosis, protection and surveillance [PDF]
: Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical modelling, monitoring, evaluation, surveillance and public ...
Bergquist, R. +6 more
core +2 more sources

