Results 61 to 70 of about 40,666 (217)

Expression of microRNA-454 in TGF-β1-stimulated hepatic stellate cells and in mouse livers infected with Schistosoma japonicum

Parasites & Vectors, 2014
Background In the process of hepatic fibrosis, hepatic stellate cells (HSCs) can be activated by many inflammatory cytokines. The transforming growth factor-β1 (TGF-β1) is one of the main profibrogenic mediators.
Dandan Zhu, Xue He, Yinong Duan, Jinling Chen, Jianxin Wang, Xiaolei Sun, Hongyan Qian, Jinrong Feng, Wei Sun, Feifan Xu, Lingbo Zhang   +10 more
doaj   +1 more source

Chronic Cholestatic Liver Disease Induced by Larval Ascariasis: Novel Insights Into Immune‐Mediated Pathogenesis and Hepatic Fibrosis in Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Liver alterations induced by single infection (SI) or reinfection (RE) with 250 or 2500 Ascaris suum eggs in mice. Histological analysis shows inflammatory cell infiltration (eosinophils, lymphocytes, macrophages, and neutrophils), fibrotic areas, and bile duct proliferation in infected animals compared with uninfected controls.
Jorge Lucas Nascimento Souza, Chiara Cássia Oliveira Amorim, Ana Rafaela Antunes‐Porto, Fernanda Rezende Souza, Evelyn Ane Oliveira, Izabela da Silva Oliveira, Isabela de Brito Duval, Andressa Mariana Saldanha‐Elias, Marcelo Eduardo Cardozo, Ramayana Morais de Medeiros Brito, Luisa Mourão Dias Magalhães, Geovanni Dantas Cassali, Neima Briggs, Ricardo Toshio Fujiwara, Remo Castro Russo, Guilherme Grossi Lopes Cançado, Lilian Lacerda Bueno   +16 more
wiley   +1 more source

The evaluation of control measures against Schistosoma mekongi in Cambodia by a mathematical model [PDF]

, 2008
We constructed a mathematical model for the transmission of Schistosoma mekongi in Cambodia. The simulation of the model will be instrumental in planning schistosomiasis control measures.
Chigusa, Yuichi, Sinuon, Muth, Kirinoki, Masashi, Socheat, Duong, Matsuda, Hajime, Ishikawa, Hirofumi, Hisakane, Naoto   +6 more
core   +1 more source

Genome-wide identification of Schistosoma japonicum microRNAs using a deep-sequencing approach. [PDF]

PLoS ONE, 2009
BackgroundHuman schistosomiasis is one of the most prevalent and serious parasitic diseases worldwide. Schistosoma japonicum is one of important pathogens of this disease.
Jian Huang, Pei Hao, Hui Chen, Wei Hu, Qing Yan, Feng Liu, Ze-Guang Han   +6 more
doaj   +1 more source

Prevalence and Associated Factor of Schistosoma Haematobium Among Primary School Children in Dubti City District, Afar, Northeast Ethiopia, 2022. “A Cross‐Sectional Study”

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Human schistosomiasis is a parasitic disease causing organ damage and developmental delays in children. Updated data on its distribution is vital for targeted interventions. This study aimed to determine the prevalence and associated factors of Schistosoma haematobium infection among school‐age children in Dubti city ...
Setitual Mesfin, Osman Ahmed, Ayenew Berhan, Andargachew Almaw, Dessie Tegegne, Getaneh Alemu, Yehunie Yirdaw, Getu Abeje   +7 more
wiley   +1 more source

iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats.

PLoS Neglected Tropical Diseases, 2022
Humans and a wide range of mammals are generally susceptible to Schistosoma infection, while some rodents such as Rattus rats and Microtus spp are not.
Jia Shen, Si-Fei Yu, Mei Peng, De-Hua Lai, Geoff Hide, Zhong-Dao Wu, Zhao-Rong Lun   +6 more
doaj   +1 more source

A Whole‐Genome Investigation of Mitonuclear Discordance in the Trematode Parasite Atriophallophorus winterbourni

Molecular Ecology, Volume 35, Issue 10, May 2026.
ABSTRACT Faster evolution of mitochondrial genomes relative to nuclear genomes creates selective pressure on nuclear genes involved in mitochondrial function to preserve mitonuclear compatibility required for energy production. In isolated populations, such coevolution occurs independently.
Natalia Zajac, Frida Feijen, Jukka Jokela   +2 more
wiley   +1 more source

Elemental concentration in Schistosoma mansoni and Schistosoma japonicum eggs.

, 2016
Elemental concentration in Schistosoma mansoni and Schistosoma japonicum eggs.
Carlos Graeff-Teixera (413382), Alexandra Suvorova (413380), Andreas Hofmann (160401), Martin Saunders (413378), Shu Q. Toh (413377), Stephan Karl (46605), Lucía Gutiérrez (413373), Roland Kerr (413375), Michael J. House (392724), Timothy G. St. Pierre (176372), Robert C. Woodward (413381), Jeremy A. Shaw (413379), Malcolm K. Jones (202746), Renata R. F. Candido (413376), Rafael Lucyk-Maurer (413374)   +14 more
core   +1 more source

Parasitic Infections and Associated Cognitive Outcome Among School‐Aged Children in Africa: A Systematic Review

Brain and Behavior, Volume 16, Issue 4, April 2026.
Parasitic infections like schistosomiasis, soil‐transmitted helminths, and malaria can impair nutrient absorption, oxygen supply, and brain function, leading to memory deficits, attention deficits, reduced intelligence quotient, weak academic performance, and motor or executive deficits.
Albertha Maku Adu, David Larbi Simpong, David Mawutor Donkor, Kwaku Sarfo Manu, Maxwell Hubert Antwi, Linus Kpelle, George Nkrumah Osei, Ansumana Bockarie   +7 more
wiley   +1 more source

Development of monoclonal antibodies against Sj29 and its possible application for schistosomiasis diagnosis

International Journal of Infectious Diseases, 2017
Objective: Timely Schistosoma japonicum detection improves outcomes in schistosomiasis. Here, we established a double antibody sandwich ELISA to detect Schistosoma japonicum.
Cui-Ping Ren, Quan Liu, Feng-Chun Liu, Feng-Yu Zhu, Shi-Xiang Cui, Zhen Liu, Wen-Da Gao, Miao Liu, Yong-Sheng Ji, Ji-Jia Shen   +9 more
doaj   +1 more source