Results 51 to 60 of about 64,678 (294)

The Differential and Dynamic Progression of Hepatic Inflammation and Immune Responses During Liver Fibrosis Induced by Schistosoma japonicum or Carbon Tetrachloride in Mice

Frontiers in Immunology, 2020
Liver fibrosis can result from various causes and could progress to cirrhosis and cancer; however, there are no effective treatments due to that its molecular mechanism is unclear. liver fibrosis model made by Schistosoma japonicum (S.
L. Song, Xu-Ren Yin, S. Mu, Jia-huang Li, Hong Gao, Ying Zhang, P. Dong, C. Mei, Z. Hua   +8 more
semanticscholar   +1 more source

Proteomic and deep sequencing analysis of extracellular vesicles isolated from adult male and female Schistosoma japonicum

PLoS Neglected Tropical Diseases, 2020
Schistosomes are the causative agent of schistosomiasis, which affects more than 200 million people worldwide. Unlike other trematode parasites, schistosomes (along with the Didymozoidae) have evolved separate sexes.
Pengfei Du, B. Giri, Juntao Liu, Tianqi Xia, C. Grevelding, G. Cheng   +5 more
semanticscholar   +1 more source

Schistosoma japonicum extracellular vesicle miRNA cargo regulates host macrophage functions facilitating parasitism

PLoS Pathogens, 2019
Schistosome infection persists for decades. Parasites are in close contact with host peripheral blood immune cells, yet little is known about the regulatory interactions between parasites and these immune cells.
Juntao Liu, Lihui Zhu, Jianbin Wang, Lin Qiu, Yongjun Chen, Richard E. Davis, G. Cheng   +6 more
semanticscholar   +1 more source

Schistosoma japonicum

Definitions, 2020
This datasheet on Schistosoma japonicum covers Identity, Distribution, Hosts/Species Affected.
Martin Nelwan
semanticscholar   +1 more source

Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors. [PDF]

, 2019
BackgroundSchistosomiasis is one of the world's most common NTDs. Successful control operations often target snail vectors with the molluscicide niclosamide.
Bu, Lijing, Buddenborg, Sarah K, Kamel, Bishoy, Loker, Eric S, Mkoji, Gerald M, Zhang, Si-Ming   +5 more
core   +2 more sources

Temporal transcriptome change of Oncomelania hupensis revealed by Schistosoma japonicum invasion

Cell & Bioscience, 2020
The freshwater snail Oncomelania hupensis is the obligate intermediate host for Schistosoma japonicum in China. Transcriptomic examination of snail–schistosome interactions can provide valuable information of host response at physiological and immune ...
Xinyu Feng, Ling-Qian Zhu, Zhiqiang Qin, X. Mo, Y. Hao, Ying Jiang, Wei Hu, Shizhu Li   +7 more
semanticscholar   +1 more source

Deficiency of PKCλ/ι alleviates the liver pathologic impairment of Schistosoma japonicum infection by thwarting Th2 response

Parasites & Vectors, 2022
Background The activation of immune response driven by the eggs of Schistosoma japonicum and the subsequent secretions is the culprit behind granulomatous inflammation and liver fibrosis.
Congjin Mei, Yingying Yang, Panpan Dong, Lijun Song, Yonghua Zhou, Yongliang Xu, Chuanxin Yu   +6 more
doaj   +1 more source

Fragment-based discovery of a regulatory site in thioredoxin glutathione reductase acting as "doorstop" for NADPH entry [PDF]

, 2018
Members of the FAD/NAD-linked reductase family are recognized as crucial targets in drug development for cancers, inflammatory disorders, and infectious diseases.
Angelucci, Francesco, Ardini, Matteo, Arner, Elias S. J., Bellelli, Andrea, Boumis, Giovanna, Chen, Qing, Fata, Francesca, Ippoliti, Rodolfo, Jadhav, Ajit, Lea, Wendy A., Lyu, Haining, Miele, Adriana E., Petukhov, Pavel A., Silvestri, Ilaria, Simeonov, Anton, Thatcher, Gregory R. J., Williams, David L.   +16 more
core   +3 more sources

Galectins, Eosinophiles, and Macrophages May Contribute to Schistosoma japonicum Egg-Induced Immunopathology in a Mouse Model

Frontiers in Immunology, 2020
Schistosomiasis is a severe public health problem, which can cause tissue fibrosis and can even be fatal. Previous studies have proven that galectins and different kinds of cells involve in the regulation of tissue fibrosis process.
Zhanhong Ye, Shiguang Huang, Yanxia Zhang, Xu Mei, Huanqin Zheng, Meiyu Li, Jianhuang Chen, Fangli Lu   +7 more
semanticscholar   +1 more source

A Case of Urogenital Human Schistosomiasis from a Non-endemic Area [PDF]

, 2015
© 2015 Calvo-Cano et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Berry, Agustín Franco, Antonia Calvo-Cano, BB Obeng, BL Webster, BL Webster, D Wichmann, David Rollinson, H Moné, JE Azar, Joaquim Gascon, Josefina Pardos, L Cnops, Lieselotte Cnops, Lisette van Lieshout, M. E. Valls, Malcolm K. Jones, MB Taberner, ML Casella, T Huyse, Tine Huyse, VR Southgate   +21 more
core   +6 more sources