Results 51 to 60 of about 15,657 (202)

Proliferation of MDSCs may indicate a lower CD4+ T cell immune response in schistosomiasis japonica

Parasite
Background: Schistosoma japonicum (S. japonicum) is the main species of Schistosoma prevalent in China. Myeloid-derived suppressor cells (MDSCs) are important immunoregulatory cells and generally expand in parasite infection, but there is little research
Peng Bo, Luo Yulin, Xie Shudong, Zhuang Quan, Li Junhui, Zhang Pengpeng, Liu Kai, Zhang Yu, Zhou Chen, Guo Chen, Zhou Zhaoqin, Zhou Jie, Cai Yu, Xia Meng, Cheng Ke, Ming Yingzi   +15 more
doaj   +1 more source

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for differential identification of adult Schistosoma worms

Parasites & Vectors, 2023
Background Schistosomiasis is a major neglected tropical disease that affects up to 250 million individuals worldwide. The diagnosis of human schistosomiasis is mainly based on the microscopic detection of the parasite’s eggs in the feces (i.e., for ...
Jurena Christiane Ebersbach, Marcello Otake Sato, Matheus Pereira de Araújo, Megumi Sato, Sören L. Becker, Issa Sy   +5 more
doaj   +1 more source

The swine flu alert: keeping Asia safe [PDF]

, 2009
After years of concern about H5N1 bird flu, the new flu causing global alarm is a pig virus of the H1N1 family. As influenza reports erupt around the world, inevitable questions are arising. Is this the big one?
Balen, J, Caballerho-Anthony, M, Chng, B
core  

Dr. Yang Zhong: an explorer on the road forever [PDF]

, 2017
On the morning of September 25th 2017, grievous news spread from the remote Ordos region of Inner Mongolia to Fudan University campus in Shanghai. Professor Yang Zhong, a famous botanist and the Dean of Fudan University’s graduate school, passed away in ...
FA Bisby, H Zeng, J Liu, K Jin, L Sun, P Hao, Q Qiao, R Luo, T Sang, The Chinese SARS Molecular Epidemiology Consortium, The Schistosoma japonicum Genome Sequencing and Functional Analysis Consortium, Y Zhong, Y Zhong, Y Zhong, Y Zhong, Y Zhong, Y Zhu   +16 more
core   +3 more sources

Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Elany B. Silva, Zhenze Jiang, Chenxi Liu, Pavla Fajtová, Thaiz R. Teixeira, Giovana de Castro Fiorini Maia, Lawrence J. Liu, Nelly El‐Sakkary, Danielle E. Skinner, Ali Syed, Steven C Wang, Conor R. Caffrey, Anthony J. O'Donoghue   +12 more
wiley   +1 more source

Role of a mouse monoclonal IgE antibody in passive transfer of immunity to Schistosoma japonicum infection

Memorias do Instituto Oswaldo Cruz, 1987
We have been able to produce a mouse monoclonal IgE antibody specific to an adult worm antigen extracted from Schistosoma japonicum (Sj). The antibody was able to elicit passive cutaneous anaphylaxis in the rat skin against Sj with the highest titer of 1:
Somei Kojima, Tuenta Janecharut, Hidekazu Hata, Munetoshi Niimura   +3 more
doaj   +1 more source

Human Schistosome Infection and Allergic Sensitisation [PDF]

, 2012
Several field studies have reported an inverse relationship between the prevalence of helminth infections and that of allergic sensitisation/atopy. Recent studies show that immune responses induced by helminth parasites are, to an extent, comparable to ...
Mutapi, Francisca, Rujeni, Nadine, Taylor, David W.   +2 more
core   +3 more sources

Tubulin Polymerization Promoting Proteins: Functional Diversity With Implications in Neurological Disorders

Journal of Neuroscience Research, Volume 103, Issue 5, May 2025.
A family of human proteins, encoded by Tubulin Polymerization Promoting Proteins (TPPP), is highly conserved across species. TPPP displays remarkable functional diversity and is implicated in various neurological disorders. Image created with BioRender.com.
Paloma J. Diaz, Qian Shi, Priscilla Y. McNeish, Swati Banerjee   +3 more
wiley   +1 more source

Genome-wide identification of Schistosoma japonicum microRNAs using a deep-sequencing approach. [PDF]

PLoS ONE, 2009
BackgroundHuman schistosomiasis is one of the most prevalent and serious parasitic diseases worldwide. Schistosoma japonicum is one of important pathogens of this disease.
Jian Huang, Pei Hao, Hui Chen, Wei Hu, Qing Yan, Feng Liu, Ze-Guang Han   +6 more
doaj   +1 more source

The in vivo transcriptome of Schistosoma mansoni in the prominent vector species Biomphalaria pfeifferi with supporting observations from Biomphalaria glabrata. [PDF]

, 2019
BackgroundThe full scope of the genes expressed by schistosomes during intramolluscan development has yet to be characterized. Understanding the gene products deployed by larval schistosomes in their snail hosts will provide insights into their ...
Bu, Lijing, Buddenborg, Sarah K, Hanelt, Ben, Kamel, Bishoy, Loker, Eric S, Mkoji, Gerald M, Zhang, Si-Ming   +6 more
core   +2 more sources