Results 1 to 10 of about 44,135 (156)

SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties. [PDF]

, 2018
BackgroundSerine proteases are important virulence factors for many pathogens. Recently, we discovered a group of trypsin-like serine proteases with domain organization unique to flatworm parasites and containing a thrombospondin type 1 repeat (TSR-1 ...
Caffrey, Conor R, Chanová, Marta, Craik, Charles S, Dvořák, Jan, Fajtová, Pavla, Horn, Martin, Hubálek, Martin, Jiang, Zhenze, Leontovyč, Adrian, Mareš, Michael, Marešová, Lucie, O'Donoghue, Anthony J, Ulrychová, Lenka, Vondrášek, Jiří   +13 more
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Chemosterilization of Schistosoma mansoni [PDF]

Nature, 1968
THE range of chemical agents which can produce sterility in experimental male rodents is gradually increasing. (For recent surveys, see Jackson1,2.) The list includes nitroaromatic compounds, for example, nitrofuranes, nitrothiazoles and nitropyrroles, besides a variety of compounds of the alkylating category.
Harold Jackson, P. Davies, Marion Bock
openaire   +3 more sources

The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni [PDF]

, 2016
Natural selection acts on all organisms, including parasites, to maximise reproductive fitness. Drug resistance traits are often associated with life-history costs in the absence of treatment.
Viana, Mafalda, Faust, Christina L., Haydon, Dan T., Webster, Joanne P., Lamberton, Poppy H.L.   +4 more
core   +13 more sources

Identification of Schistosoma mansoni microRNAs [PDF]

BMC Genomics, 2011
Abstract Background MicroRNAs (miRNAs) constitute a class of single-stranded RNAs which play a crucial role in regulating development and controlling gene expression by targeting mRNAs and triggering either translation repression or messenger RNA (mRNA) degradation. miRNAs are widespread in eukaryotes and to date over
Gustavo C. Cerqueira, Gustavo C. Cerqueira, Andrew R. Dalby, Philip T. LoVerde, Jonathan M. Lee, Appolinaire Djikeng, Appolinaire Djikeng, Adhemar Zerlotini, Adhemar Zerlotini, Rosiane A. Silva-Pereira, Najib M. El-Sayed, Guilherme Oliveira, Mariana Simoes, Mariana Simoes   +13 more
openaire   +6 more sources

Schistosoma mansoni associated glomerulopathy [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1999
(1)Institute of Tropical Medicine, Sao Paulo, SP, Brasil. (2)Division of Nephrology, “Hospital das Clinicas”, University of S. Paulo, Medical School, S. Paulo, SP, Brasil. (3)Sao Paulo Federal University Medical School, Dept. of Microbiology, Immunology, and Parasitology, S. Paulo, SP, Brazil. Correspondence to: Dr. Thales De Brito, Av. Dr.
BRITO, T. DE, NUSSENZVEIG, I., CARNEIRO, Célia R.W., SILVA, Ana Maria G.   +3 more
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Imatinib activity on Schistosoma mansoni [PDF]

Memórias do Instituto Oswaldo Cruz, 2013
Imatinib, a drug used for treatment of human chronic myeloid leukaemia, due to its activity against protein kinases, has been also evaluated in vitro against Schistosoma mansoni showing high schistosomicidal activity. In the present experiments imatinib activity in vitro was confirmed at the doses of 25 µM, 50 µM and 100 µM.
Katz, Naftale, Couto, Flávia Fernanda Bubulo, Araújo, Neusa   +2 more
openaire   +4 more sources

Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs [PDF]

, 2009
Treatment with praziquantel (PZQ) has become virtually the sole basis of schistosomiasis control in sub-Saharan Africa and elsewhere, and the drug is reviewed here in the context of the increasing rate that it is being used for this purpose. Attention is
A. MBAYE, Alonso, Baard, Barakat, Botros, Botros, Cioli, D. CIOLI, D. ENGELS, G. COLES, Keiser, L. A. TCHUEM TCHUENTÉ, L. PICA-MATTOCCIA, M. J. DOENHOFF, Mwanakasale, N'Goran, P. HAGAN, Pica-Mattoccia, S. BOTROS, Stohler, Utzinger, V. SOUTHGATE, Van Wyk   +22 more
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Intestinal parasitic infections in schoolchildren in different settings of Côte d'Ivoire : effect of diagnostic approach and implications for control [PDF]

, 2012
BACKGROUND: Social-ecological systems govern parasitic infections in humans. Within the frame of assessing the accuracy of a rapid diagnostic test for Schistosoma mansoni in Cote d'Ivoire, three different endemicity settings had to be identified and ...
AS Stensgaard, B Matthys, CH King, D Glinz, Dimitri Hauri, Eliézer K N’Goran, G Raso, J Aagaard-Hansen, J Keiser, J Keiser, J Utzinger, J Utzinger, J Vercruysse, Jean T Coulibaly, JT Coulibaly, Jürg Utzinger, K Ziegelbauer, Kigbafori D Silué, LD Wang, LT Tchuem Tchuenté, M Booth, M Nacher, M Ouattara, Mamadou Ouattara, MJ Enk, N Katz, N Yakubu, NA N'Guessan, P Druilhe, P Hotez, P Steinmann, P Steinmann, PJ Hotez, PJ Hotez, PJ Hotez, R Pullan, RN Chunge, S Brooker, S Knopp, SG Traoré, SJ de Vlas, SL Stanley, SO Asaolu, Stefanie Knopp, T Minenoa, Thomas Fürst, TW Mwangi, WHO, WHO, YX Huang   +49 more
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Chlorination of Schistosoma mansoni cercariae

PLOS Neglected Tropical Diseases, 2020
Schistosomiasis is a water-based disease acquired through contact with cercaria-infested water. Communities living in endemic regions often rely on parasite-contaminated freshwater bodies for their daily water contact activities, resulting in recurring schistosomiasis infection.
Laura Braun, Yasinta Daniel Sylivester, Meseret Dessalegne Zerefa, Muluwork Maru, Fiona Allan, Feleke Zewge, Aidan M. Emery, Safari Kinung’hi, Michael R. Templeton   +8 more
openaire   +7 more sources

Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees [PDF]

, 2001
The radiation-attenuated Schistosoma mansoni vaccine is highly effective in rodents and primates but has never been tested in humans, primarily for safety reasons.
Abe K., Agnew A., Amory Soisson L., Aranda-Michel J., Araújo M. I., Ashton P. D., Bergquist N. R., Butterworth A. E., Butterworth A. E., Caldas I. R., Capron A., Carneiro-Santos P., Caulada-Benedetti Z., Chan M. S., Coulson P. S., de Clercq D., de Jonge N., Deelder A. M., Doetze A., Dunne D. W., Eberl M., Eberl M., Eberl M., Gryseels B, Gryseels B., Grzych J. M., Harrop R., Harrop R., Hsü S. Y., Jankovic D., Kardorff R., Kasper G., Katz N., Kuntz R. E., Mahmoud O. M., Malaquias L. C. C., Mansour M. M., Marguerite M., Medhat A., Montenegro S. M. L., Moser D., Olsen A., Omer F. M., Omer-Ali P., Pearce E. J., Pemberton R. M., Polman K., Prince A. M., Renquist D. M., Rieckmann K. H., Rocha M. O., Sadun E. H., Sadun E. H., Sher A., Smythies L. E., Sundstedt A., Tanner M., Velupillai P., Viana I. R., Viana I. R., von Lichtenberg F., von Lichtenberg F., Williams M. E., Wilson R. A., Yole D. S., Yole D. S.   +65 more
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