Results 1 to 10 of about 66,712 (259)

Schistosoma mansoni.

Trends in Parasitology, 2020
proteinase similar to mammalian lysosomal cathepsin B, proposed to be a key enzyme in schistosome metabolism. Protein Sm32 has been identified as a putative cysteine proteinase termed a 'haemoglobinase'.
Timothy J C Anderson, Egie E Enabulele
semanticscholar   +6 more sources

Non-typhoidal Salmonella intestinal carriage in a Schistosoma mansoni endemic community in a rural area of the Democratic Republic of Congo

PLoS Neglected Tropical Diseases, 2020
Background Clinical observations and animal studies have suggested that Salmonella intestinal carriage is promoted by concurrent Schistosoma infection.
Lisette Mbuyi-Kalonji, B. Barbé, Gaëlle Nkoji, J. Madinga, Clémentine Roucher, Sylvie Linsuke, Marie R. G. Hermy, Anne-Sophie Heroes, W. Mattheus, K. Polman, P. Lutumba, Marie-France Phoba, O. Lunguya, J. Jacobs   +13 more
semanticscholar   +2 more sources

Unveiling the anti-neoplastic potential of Schistosoma mansoni-derived antigen against breast cancer: a pre-clinical study [PDF]

European Journal of Medical Research
Background Cancer is a global health concern, with millions of new cases and deaths annually. Recently, immunotherapy has strengthened cancer treatment by harnessing the body's immune system to fight cancer. The search for advanced cancer immunotherapies
Maha Mohamed Eissa, Sonia Rifaat Ahmed Allam, Cherine Adel Ismail, Rasha Abdelmawla Ghazala, Nahla El Skhawy, Inass Ibrahim Ahmed Zaki, Eman Ibrahim El-said Ibrahim   +6 more
doaj   +2 more sources

Biochemical, coagulation, and platelet count profiles among Schistosoma mansoni infected patients attending at selected Dembiya health institutions, Northwest Ethiopia [PDF]

BMC Microbiology
Background Schistosomiasis is a parasitic disease that causes coagulation disorders and biochemical abnormalities. This is due to liver failure, platelet destruction, disruption of blood flow, and endothelial function by the schistosomes.
Wagaw Abebe, Wossenseged Lemma, Yalewayker Tegegne, Assefa Sisay, Tadesse Misganaw, Sisay Ayana, Desie Kasew, Marye Nigatie Debash, Alemu Birara Zemariam, Tadele Emagneneh, Adane Derso   +10 more
doaj   +2 more sources

Does Schistosoma Mansoni Facilitate Carcinogenesis?

Cells, 2021
Schistosomiasis is one of the most prominent parasite-induced infectious diseases, causing tremendous medical and socioeconomic problems. Current studies have reported on the spread of endemic regions and the fear of development of resistance against ...
V. von Bülow, J. Lichtenberger, C. Grevelding, Franco H Falcone, E. Roeb, M. Roderfeld   +5 more
semanticscholar   +1 more source

A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding

Science, 2020
Schistosome biology illuminated Schistosomiasis is caused by a parasitic flatworm about which little is known. Therefore, options to combat human disease caused by schistosome infection are limited.
George R. Wendt, Lu Zhao, Rui Chen, Chenxi Liu, A. O’Donoghue, C. Caffrey, M. Reese, J. Collins   +7 more
semanticscholar   +1 more source

Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni

Science, 2020
Schistosome biology illuminated Schistosomiasis is caused by a parasitic flatworm about which little is known. Therefore, options to combat human disease caused by schistosome infection are limited.
Jipeng Wang, Carlos Paz, G. Padalino, Avril Coghlan, Zhigang Lu, I. Grădinaru, Julie N. R. Collins, M. Berriman, K. Hoffmann, James J. Collins   +9 more
semanticscholar   +1 more source

Multihost Transmission of Schistosoma mansoni in Senegal, 2015–2018

Emerging Infectious Diseases, 2020
In West Africa, Schistosoma spp. are capable of infecting multiple definitive hosts, a lifecycle feature that may complicate schistosomiasis control. We characterized the evolutionary relationships among multiple Schistosoma mansoni isolates collected ...
S. Catalano, E. Léger, C. Fall, A. Borlase, S. Diop, Duncan J. Berger, B. Webster, B. Faye, Nicolas D. Diouf, D. Rollinson, Mariama Sène, K. Bâ, J. Webster   +12 more
semanticscholar   +1 more source

Effects of Water Source, Sanitation and Hygiene on the Prevalence of Schistosoma mansoni among School Age Children in Jawe District, Northwest Ethiopia

Iranian Journal of Parasitology, 2020
Background: Intestinal schistosomiasis is a disease caused by infection with one of the blood flukes called Schistosoma mansoni. The distribution of Schistosoma mansoni infection is high in Sub-Saharan Africa due to water source, sanitation and hygiene ...
Tadesse HAILU, Wondemagegn MULU, Bayeh ABERA   +2 more
doaj   +1 more source

Granuloma formation and tissue pathology in Schistosoma japonicum versus Schistosoma mansoni infections

Parasite immunology (Print), 2020
Schistosomiasis is the most important helminth disease in the world from a public health perspective. S mansoni and S japonicum account for the majority of global intestinal schistosomiasis cases, and the pathogenesis is widely assumed to be ...
Felix Llanwarne, H. Helmby
semanticscholar   +1 more source