proteinase similar to mammalian lysosomal cathepsin B, proposed to be a key enzyme in schistosome metabolism. Protein Sm32 has been identified as a putative cysteine proteinase termed a 'haemoglobinase'.
Timothy J C Anderson, Egie E Enabulele
semanticscholar +6 more sources
BACKGROUND:Clinical observations and animal studies have suggested that Salmonella intestinal carriage is promoted by concurrent Schistosoma infection.
Lisette Mbuyi-Kalonji+13 more
doaj +2 more sources
Objective The aim of this study was to determine the magnitude of Schistosoma mansoni and its associated risk factors in the study area. Results Of 422 school children, 223 (52.8%) and 199 (47.2%) were males and females, respectively.
Lemma Workineh+3 more
doaj +2 more sources
Prevalence of malaria and Schistosoma mansoni coinfection in sub Saharan Africa: A systematic review and meta-analysis [PDF]
Background: Malaria and schistosomiasis are two parasite illnesses that share transmission sites in distinct tropical climates. Malaria-schistosomiasis coinfection is widespread in Africa.
Wagaw Abebe+9 more
doaj +2 more sources
A survey of the prevalence of Schistosomiasis among pupils in Apata and Laranto areas in Jos, Plateau State [PDF]
Prevalence of Schistosomiasis in apparently healthy primary school pupils in Apata and Laranto areas of Jos was surveyed using 300 samples of stool and 300 samples of urine.
Okpala HO+5 more
doaj +1 more source
Unveiling the anti-neoplastic potential of Schistosoma mansoni-derived antigen against breast cancer: a pre-clinical study [PDF]
Background Cancer is a global health concern, with millions of new cases and deaths annually. Recently, immunotherapy has strengthened cancer treatment by harnessing the body's immune system to fight cancer. The search for advanced cancer immunotherapies
Maha Mohamed Eissa+6 more
doaj +2 more sources
Does Schistosoma Mansoni Facilitate Carcinogenesis?
Schistosomiasis is one of the most prominent parasite-induced infectious diseases, causing tremendous medical and socioeconomic problems. Current studies have reported on the spread of endemic regions and the fear of development of resistance against ...
V. von Bülow+5 more
semanticscholar +1 more source
Sensitivity and Specificity of Multiple Kato-Katz Thick Smears and a Circulating Cathodic Antigen Test for Schistosoma mansoni Diagnosis Pre- and Post-repeated-Praziquantel Treatment [PDF]
Two Kato-Katz thick smears (Kato-Katzs) from a single stool are currently recommended for diagnosing Schistosoma mansoni infections to map areas for intervention. This ‘gold standard’ has low sensitivity at low infection intensities.
A Koukounari+56 more
core +18 more sources
A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding
Schistosome biology illuminated Schistosomiasis is caused by a parasitic flatworm about which little is known. Therefore, options to combat human disease caused by schistosome infection are limited.
George R. Wendt+7 more
semanticscholar +1 more source
The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni [PDF]
Natural selection acts on all organisms, including parasites, to maximise reproductive fitness. Drug resistance traits are often associated with life-history costs in the absence of treatment.
Viana, Mafalda+4 more
core +9 more sources