Results 11 to 20 of about 66,712 (259)

Pharmacological Inhibition of c-Jun N-Terminal Kinase Activity Exacerbates Liver Damage in Schistosoma mansoni Infected Mice. [PDF]

Liver Int
ABSTRACT Background and Aims Schistosomiasis is a neglected tropical disease affecting more than 250 million people worldwide. Eggs of the parasitic helminth S. mansoni cause major morbidity in the liver, spleen and intestine. Of note, egg‐released soluble antigens (SEA) induce the transcription factor c‐Jun in hepatocytes, promoting hepatocellular ...
Stettler F, Knedla L, Hagen M, von Bülow V, Müller H, Tschuschner A, Zahner D, Haeberlein S, Moescheid MF, Windhorst A, Burg-Roderfeld M, Glebe D, Moreira BP, Lesieur C, Schmid A, Falcone FH, Grevelding CG, Roeb E, Roderfeld M.   +18 more
europepmc   +2 more sources

Chemosterilization of Schistosoma mansoni [PDF]

Nature, 1968
THE range of chemical agents which can produce sterility in experimental male rodents is gradually increasing. (For recent surveys, see Jackson1,2.) The list includes nitroaromatic compounds, for example, nitrofuranes, nitrothiazoles and nitropyrroles, besides a variety of compounds of the alkylating category.
Harold Jackson, P. Davies, Marion Bock
openaire   +3 more sources

Identification of Schistosoma mansoni microRNAs [PDF]

BMC Genomics, 2011
Abstract Background MicroRNAs (miRNAs) constitute a class of single-stranded RNAs which play a crucial role in regulating development and controlling gene expression by targeting mRNAs and triggering either translation repression or messenger RNA (mRNA) degradation. miRNAs are widespread in eukaryotes and to date over
Gustavo C. Cerqueira, Gustavo C. Cerqueira, Andrew R. Dalby, Philip T. LoVerde, Jonathan M. Lee, Appolinaire Djikeng, Appolinaire Djikeng, Adhemar Zerlotini, Adhemar Zerlotini, Rosiane A. Silva-Pereira, Najib M. El-Sayed, Guilherme Oliveira, Mariana Simoes, Mariana Simoes   +13 more
openaire   +6 more sources

Characteristics of persistent hotspots of Schistosoma mansoni in western Côte d’Ivoire

Parasites & Vectors, 2020
Preventive chemotherapy with praziquantel is the cornerstone of schistosomiasis control. However, in some social-ecological settings, the prevalence and/or intensity of Schistosoma infection does not lower meaningfully despite multiple rounds of ...
Rufin K Assaré, R. N. N’Tamon, L. Bellai, Judicaelle A. Koffi, T. Mathieu, M. Ouattara, Eveline Hürlimann, J. Coulibaly, S. Diabaté, E. N'Goran, J. Utzinger   +10 more
semanticscholar   +1 more source

Schistosoma mansoni associated glomerulopathy [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1999
(1)Institute of Tropical Medicine, Sao Paulo, SP, Brasil. (2)Division of Nephrology, “Hospital das Clinicas”, University of S. Paulo, Medical School, S. Paulo, SP, Brasil. (3)Sao Paulo Federal University Medical School, Dept. of Microbiology, Immunology, and Parasitology, S. Paulo, SP, Brazil. Correspondence to: Dr. Thales De Brito, Av. Dr.
BRITO, T. DE, NUSSENZVEIG, I., CARNEIRO, Célia R.W., SILVA, Ana Maria G.   +3 more
openaire   +5 more sources

Imatinib activity on Schistosoma mansoni [PDF]

Memórias do Instituto Oswaldo Cruz, 2013
Imatinib, a drug used for treatment of human chronic myeloid leukaemia, due to its activity against protein kinases, has been also evaluated in vitro against Schistosoma mansoni showing high schistosomicidal activity. In the present experiments imatinib activity in vitro was confirmed at the doses of 25 µM, 50 µM and 100 µM.
Katz, Naftale, Couto, Flávia Fernanda Bubulo, Araújo, Neusa   +2 more
openaire   +4 more sources

Development of a laboratorial platform for diagnosis of schistosomiasis mansoni by PCR-ELISA

BMC Research Notes, 2018
Objective We developed a laboratorial platform to release a commercial platform used in the PCR-ELISA for the molecular diagnosis of schistosomiasis mansoni.
Carolina Senra, Luciana Inácia Gomes, Liliane Maria Vidal Siqueira, Paulo Marcos Zech Coelho, Ana Rabello, Edward Oliveira   +5 more
doaj   +1 more source

Chlorination of Schistosoma mansoni cercariae

PLOS Neglected Tropical Diseases, 2020
Schistosomiasis is a water-based disease acquired through contact with cercaria-infested water. Communities living in endemic regions often rely on parasite-contaminated freshwater bodies for their daily water contact activities, resulting in recurring schistosomiasis infection.
Laura Braun, Yasinta Daniel Sylivester, Meseret Dessalegne Zerefa, Muluwork Maru, Fiona Allan, Feleke Zewge, Aidan M. Emery, Safari Kinung’hi, Michael R. Templeton   +8 more
openaire   +7 more sources

The association of Schistosoma mansoni infection with hepatocellular carcinoma

Revista da Sociedade Brasileira de Medicina Tropical, 1984
The association of Schistosoma mansoni infection with hepatocellular carcinoma (HCC) was studied in Espirito Santo State, Brazil. Schistosoma infection was diagnosed by stool examinations or by histological finding at autopsy. HCC was diagnosed by biopsy,
Fausto Edmundo Lima Pereira, Carlos Sandoval Gonçalves   +1 more
doaj   +3 more sources

The magnitude of Schistosoma mansoni and its associated risk factors among Sebatamit primary school children, rural Bahir Dar, Northwest Ethiopia: a cross-sectional study

BMC Research Notes, 2019
Objective The aim of this study was to determine the magnitude of Schistosoma mansoni and its associated risk factors in the study area. Results Of 422 school children, 223 (52.8%) and 199 (47.2%) were males and females, respectively.
Lemma Workineh, Mulat Yimer, Woyneshet Gelaye, Desalegn Muleta   +3 more
doaj   +1 more source