The in vivo transcriptome of Schistosoma mansoni in the prominent vector species Biomphalaria pfeifferi with supporting observations from Biomphalaria glabrata. [PDF]
BackgroundThe full scope of the genes expressed by schistosomes during intramolluscan development has yet to be characterized. Understanding the gene products deployed by larval schistosomes in their snail hosts will provide insights into their ...
Bu, Lijing+6 more
core +2 more sources
Characterization, cloning and immunogenicity of antigens released by transforming cercariae of Schistosoma mansoni [PDF]
A schistosome infection is initiated when the parasite penetrates the skin of a susceptible host. Relatively large quantities of protein are released by transforming cercariae compared to later larval stages.
Coulson, P.S.+4 more
core +1 more source
Differentiation of Schistosoma haematobium from related schistosomes by PCR amplifying an inter-repeat sequence. [PDF]
Schistosoma haematobium infects nearly 150 million people, primarily in Africa, and is transmitted by select species of local bulinid snails. These snails can host other related trematode species as well, so that effective detection and monitoring of ...
Abbasi, Ibrahim+5 more
core +1 more source
Antibodies to glycans dominate the host response to schistosome larvae and eggs: Is their role protective or subversive? [PDF]
Multiple exposures of chimpanzees to the radiation-attenuated schistosome vaccine provoked a strong parasite-specific cellular and humoral immune response. Specific IgM and IgG were directed mainly against glycans on antigens released by cercariae; these
Coulson, P.S.+7 more
core +1 more source
Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors. [PDF]
BackgroundSchistosomiasis is one of the world's most common NTDs. Successful control operations often target snail vectors with the molluscicide niclosamide.
Bu, Lijing+5 more
core +2 more sources
New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel [PDF]
By 2020, the global health community aims to control and eliminate human helminthiases, including schistosomiasis in selected African countries, principally by preventive chemotherapy (PCT) through mass drug administration (MDA) of anthelminthics ...
A Danso-Appiah+75 more
core +4 more sources
Hybridisations within the genus Schistosoma: implications for evolution, epidemiology and control [PDF]
SUMMARYHybridization of parasites is an emerging public health concern in our changing world. Hybridization and introgression in parasites and pathogens can have major impacts on the host and the epidemiology and evolution of disease.
Leger, E, Webster, J P
core +1 more source
Schistosoma mansoni and membranous nephropathy [PDF]
Figure 2 | Ultrastructural findings showing glomerular capillaries with subepithelial and intramembranous electron-dense deposits besides intervening projections (spikes) regularly distributed on the glomerular basement membrane. Original magnification 8000. A 53-year-old Brazilian man presented with lower limb edema that progressed to anasarca. He had
Cristiane B. Dias+8 more
openaire +2 more sources
The protein antigens secreted in vivo by adult male Schistosoma mansoni [PDF]
Adult schistosomes can be transferred surgically from donor C57BL/6 mice to the portal veins of naive recipients with complete success. This procedure bypasses larval development and the antibody response of the host is directed against, and can be used ...
Cutts, L., Wilson, R.A.
core +1 more source
Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas [PDF]
Background: Point-of-care (POC) tests for diagnosing schistosomiasis include tests based on circulating antigen detection and urine reagent strip tests.
Bossuyt, P.M.M.+8 more
core +3 more sources